ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Vouhe, P. R.
Right arrow Articles by Kachaner, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Vouhe, P. R.
Right arrow Articles by Kachaner, J.

The Annals of Thoracic Surgery, Vol 56, 1239-1247, Copyright © 1993 by The Society of Thoracic Surgeons

ARTICLES

Pediatric cardiac transplantation for congenital heart defects: surgical considerations and results

PR Vouhe, D Tamisier, J Le Bidois, D Sidi, P Mauriat, P Pouard, D Lefebvre, SB Albanese, W Khoury and J Kachaner
Department of Cardiovascular Surgery, Laennec Hospital, Paris, France.

Among 54 children who underwent 55 heart transplantations, 24 (44%) (mean age, 4.9 +/- 4.8 years; range, 9 days to 18 years) had congenital defects with the following diagnoses: single-ventricle variants (6), hypoplastic left heart syndrome variants (5), transposition complex (6), and miscellaneous defects (7). Twenty patients (83%) had undergone 43 prior operations. Additional surgical procedures included repositioning of transposed great arteries (11), reconstruction of the aortic pathway (4), reconstruction of the pulmonary pathway (8), correction of situs inversus (1), and correction of anomalous pulmonary (1) or systemic (1) venous drainage. Reconstructive procedures were performed using donor or recipient tissue or both. There were six early deaths (hyperacute rejection, 1 patient; pulmonary hypertension, 1; graft failure, 2 patients; infection, 2) and six late deaths (sudden death, 2; chronic rejection, 2; nonspecific graft dysfunction, 1; lymphoproliferative disease, 1). The survival rate was 43% +/- 12% at 3 years. No deaths were related to surgical technique. Survival was not significantly different in pediatric recipients with cardiomyopathy (67% +/- 9%; p = 0.22). Accelerated coronary artery disease was noted in 4 operative survivors (22%; 70% confidence limits, 12% to 36%). All late survivors were free from cardiac symptoms after a mean follow-up of 34 +/- 24 months (range, 6 to 71 months). Based on this study, we reached three conclusions. (1) Careful planning of both harvesting and transplantation procedures allows heart transplantation in recipients with congenital heart diseases. (2) The surgical technique may be demanding, but the early risk is not increased.(ABSTRACT TRUNCATED AT 250 WORDS)


This article has been cited by other articles:


Home page
 Ann. Thorac. Surg.Home page
Y. S. Tjang, U. Blanz, L. Hornik, G. Tenderich, M. Morshuis, H. Stenlund, A. Bairaktaris, and R. Korfer
Heart Transplantation in Children: Clinical Outcomes in a Single Center
Ann. Thorac. Surg., November 1, 2007; 84(5): 1640 - 1644.
[Abstract] [Full Text] [PDF]

Home page
 MMCTSHome page
O. Raisky, D. Tamisier, and P. R. Vouhe
Orthotopic heart transplantation for congenital heart defects: anomalies of the systemic venous return
MMCTS, October 9, 2006; 2006(1009): 1578.
[Abstract] [Full Text] [PDF]

Home page
 MMCTSHome page
O. Raisky, D. Tamisier, and P. R. Vouhe
Orthotopic heart transplantation for congenital heart defects: situs inversus
MMCTS, October 9, 2006; 2006(1009): 1586.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
A.-R. Hosseinpour, S. Cullen, and V. T. Tsang
Transplantation for adults with congenital heart disease.
Eur. J. Cardiothorac. Surg., September 1, 2006; 30(3): 508 - 514.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
K. A. Jayakumar, L. J. Addonizio, M. R. Kichuk-Chrisant, M. E. Galantowicz, J. M. Lamour, J. M. Quaegebeur, and D. T. Hsu
Cardiac transplantation after the Fontan or Glenn procedure
J. Am. Coll. Cardiol., November 16, 2004; 44(10): 2065 - 2072.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
J. M. Chen, R. R. Davies, S. R. Mital, M. L. Mercando, L. J. Addonizio, S. P. Pinney, D. T. Hsu, J. M. Lamour, J. M. Quaegebeur, and R. S. Mosca
Trends and Outcomes in Transplantation for Complex Congenital Heart Disease: 1984 to 2004
Ann. Thorac. Surg., October 1, 2004; 78(4): 1352 - 1361.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
G. Michielon, F. Parisi, D. Di Carlo, C. Squitieri, A. Carotti, M. Buratta, and R. M. Di Donato
Orthotopic heart transplantation for failing single ventricle physiology
Eur. J. Cardiothorac. Surg., October 1, 2003; 24(4): 502 - 510.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
T. Wittwer, K. Pethig, M. Struber, M. Hoeper, W. Harringer, A. Haverich, U. Franke, and T. Wahlers
Aerosolized iloprost for severe pulmonary hypertension as a bridge to heart transplantation
Ann. Thorac. Surg., March 1, 2001; 71(3): 1004 - 1006.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
E. Malec, K. Januszewska, J. Kolcz, and J. Pajak
Factors influencing early outcome of Norwood procedure for hypoplastic left heart syndrome
Eur. J. Cardiothorac. Surg., August 1, 2000; 18(2): 202 - 206.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
J. M. Lamour, L. J. Addonizio, M. E. Galantowicz, J. M. Quaegebeur, D. M. Mancini, M. R. Kichuk, A. Beniaminovitz, R. E. Michler, A. Weinberg, and D. T. Hsu
Outcome After Orthotopic Cardiac Transplantation in Adults With Congenital Heart Disease
Circulation, November 9, 1999; 100(90002): II-200 - 205.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
K. R. Kanter, V. K.H. Tam, R. N. Vincent, A. R. Cuadrado, A. A. Raviele, and A. M. Berg
Current results with pediatric heart transplantation
Ann. Thorac. Surg., August 1, 1999; 68(2): 527 - 530.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
R. Hetzer, E. V. Potapov, J. Muller, M. Loebe, M. Hummel, Y. Weng, H. Warnecke, and P. E. Lange
Daily noninvasive rejection monitoring improves long-term survival in pediatric heart transplantation
Ann. Thorac. Surg., October 1, 1998; 66(4): 1343 - 1349.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
L. A. Vricella, A. J. Razzouk, S. R. Gundry, R. L. Larsen, M. A. Kuhn, and L. L. Bailey
Heart transplantation in infants and children with situs inversus
J. Thorac. Cardiovasc. Surg., July 1, 1998; 116(1): 82 - 86.
[Abstract] [Full Text]

Home page
 Ann. Thorac. Surg.Home page
D. A. Fullerton, D. N. Campbell, S. D. Jones, J. Jaggers, J. M. Brown, M. M. Wollmering, F. L. Grover, C. Mashburn, M. Luna, H. M. Sondheimer, et al.
Heart Transplantation in Children and Young Adults: Early and Intermediate-Term Results
Ann. Thorac. Surg., April 1, 1995; 59(4): 804 - 811.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 1993 by The Society of Thoracic Surgeons.