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The Annals of Thoracic Surgery, Vol 56, 1141-1147, Copyright © 1993 by The Society of Thoracic Surgeons
RM Bojar, H Rastegar, DD Payne, CA Mack and SL Schwartz
Because of concerns about the hemodynamic performance of 19-mm porcine
valves, we retrospectively reviewed the clinical results and
echocardiographic studies of 52 consecutive patients who received a 19- mm
Carpentier-Edwards porcine bioprosthesis (model 2625) for aortic valve
replacement from 1986 through 1991. Nearly 87% of the patients were women,
the mean age was 69 years, and the mean body surface area was 1.63 +/- 0.27
m2. Seventy-three percent of the patients had pure aortic stenosis, 96%
were in New York Heart Association classes III and IV, and 56% underwent
urgent or emergent operation. Overall hospital mortality was 7.7% with a
late mortality of 8.3% at a mean follow-up of 25 +/- 18 months. No patient
experienced a valve-related complication, and 95% of surviving patients
were in New York Heart Association classes I and II. Two-dimensional and
Doppler echocardiography performed during the first postoperative week
revealed a maximal instantaneous gradient of 44.7 +/- 13.0 mm Hg. In 43
patients for whom additional data were available, the mean gradient was
26.4 +/- 8.2 mm Hg with an effective orifice area of 0.85 +/- 0.18 cm2.
This study defines the normal range of postoperative gradients across the
19-mm Carpentier-Edwards porcine valve and demonstrates that patients
receiving this valve can achieve significant clinical improvement despite
the presence of high transvalvular gradients measured by echocardiography.
ARTICLES
Clinical and hemodynamic performance of the 19-mm Carpentier-Edwards porcine bioprosthesis
Department of Surgery (Cardiothoracic), New England Medical Center, Boston, MA 02111.
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