ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
Raymund J. Donnelly
Richard G. Berrisford
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Donnelly, R. J.
Right arrow Articles by Evans, C. C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Donnelly, R. J.
Right arrow Articles by Evans, C. C.

Ann Thorac Surg 1993;56:1029-1034
© 1993 The Society of Thoracic Surgeons

Articles

Simultaneous tracheal and esophageal pH monitoring: Investigating reflux-associated asthma

Raymund J. Donnelly, FRCSE*, Richard G. Berrisford, FRCS, Catherine I.A. Jack, MRCP, Jane A. Tran, BTech, Chistopher C. Evans, FRCP

The Cardiothioracic Centre, Liverpool, United Kingdom

* Address reprint requests to Mr Donnelly, The Cardiothoracic Centre, Thomas Drive, Liverpool, United Kingdom L14 3PE.

Aspiration of gastric acid into the trachea may cause asthma in some patients who have gastroesophageal reflux. Antireflux surgery has been advocated for such patients, but lack of an objective test for add aspiration makes patient selection difficult. We report a new technique for demonstrating acid aspiration, simultaneous tracheal and esophageal pH monitoring. Tracheal pH was measured with a 1.0-mm pH electrode introduced through the cricothyroid membrane under bronchoscopic vision. A standard esophageal pH electrode was placed in the usual position. Tracheal and esophageal pH were monitored over a 24-hour period. Peak expiratory flow rate was measured hourly while the patient was awake. We present data obtained in 3 patients with severe asthma and symptomatic gastroesophageal reflux. All 3 patients demonstrated a decrease in tracheal pH to less than 5.5, coinciding with a decrease in esophageal pH to less than 4.0. The test was repeated after antireflux operation and showed that significant decreases in esophageal pH no longer lowered tracheal pH. Asthmatic symptoms were improved, and medication was reduced in 2 of the 3 patients.




This article has been cited by other articles:


Home page
 Am. J. Respir. Crit. Care Med.Home page
E. Savarino, M. Bazzica, P. Zentilin, D. Pohl, A. Parodi, G. Cittadini, S. Negrini, F. Indiveri, R. Tutuian, V. Savarino, et al.
Gastroesophageal Reflux and Pulmonary Fibrosis in Scleroderma: A Study Using pH-Impedance Monitoring
Am. J. Respir. Crit. Care Med., March 1, 2009; 179(5): 408 - 413.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
R. P. Boesch, C. Daines, J. P. Willging, A. Kaul, A. P. Cohen, R. E. Wood, and R. S. Amin
Advances in the diagnosis and management of chronic pulmonary aspiration in children
Eur. Respir. J., October 1, 2006; 28(4): 847 - 861.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
A. O. Paget-Brown, L. Ngamtrakulpanit, A. Smith, D. Bunyan, S. Hom, A. Nguyen, and J. F. Hunt
Normative Data for pH of Exhaled Breath Condensate
Chest, February 1, 2006; 129(2): 426 - 430.
[Abstract] [Full Text] [PDF]

Home page
 Postgrad. Med. J.Home page
J L Mathew, M Singh, and S K Mittal
Gastro-oesophageal reflux and bronchial asthma: current status and future directions
Postgrad. Med. J., December 1, 2004; 80(950): 701 - 705.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
N. M. Agnew, J. B. Kendall, M. Akrofi, J. Tran, A. S. Soorae, R. Page, G. N. Russell, and S. H. Pennefather
Gastroesophageal Reflux and Tracheal Aspiration in the Thoracotomy Position: Should Ranitidine Premedication be Routine?
Anesth. Analg., December 1, 2002; 95(6): 1645 - 1649.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
T. O. Kiljander, E.-R. M. Salomaa, E. K. Hietanen, and E. O. Terho
Gastroesophageal Reflux in Asthmatics: A Double-Blind, Placebo-Controlled Crossover Study With Omeprazole
Chest, November 1, 1999; 116(5): 1257 - 1264.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
S. K. Field
A Critical Review of the Studies of the Effects of Simulated or Real Gastroesophageal Reflux on Pulmonary Function in Asthmatic Adults
Chest, March 1, 1999; 115(3): 848 - 856.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
R. W. TOBIN, C. E. POPE II, C. A. PELLEGRINI, M. J. EMOND, J. SILLERY, and G. RAGHU
Increased Prevalence of Gastroesophageal Reflux in Patients with Idiopathic Pulmonary Fibrosis
Am. J. Respir. Crit. Care Med., December 1, 1998; 158(6): 1804 - 1808.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
F. B. Sant'Ambrogio, G. Sant'Ambrogio, and K. Chung
Effects of HCl-pepsin laryngeal instillations on upper airway patency-maintaining mechanisms
J Appl Physiol, April 1, 1998; 84(4): 1299 - 1304.
[Abstract] [Full Text] [PDF]

Home page
 Arch Intern MedHome page
W. G. Simpson
Gastroesophageal Reflux Disease and Asthma: Diagnosis and Management
Arch Intern Med, April 24, 1995; 155(8): 798 - 803.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 1993 by The Society of Thoracic Surgeons.