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The Annals of Thoracic Surgery, Vol 56, 462-468, Copyright © 1993 by The Society of Thoracic Surgeons
JM Kratz, FA Crawford Jr, RM Sade, AJ Crumbley and MR Stroud
From January 1, 1979 through December 1990, 456 adult patients underwent
isolated aortic (AVR) (254) or mitral (MVR) (202) valve replacement with
the St. Jude prosthesis at the Medical University of South Carolina. Age
ranged from 21 to 84 years (mean: 54 +/- 15 years for AVR; 51 +/- 13 years
for MVR). Male sex predominated in the AVR group (66%) and female sex in
the MVR group (64%). Ninety-two patients (20%) had associated coronary
artery bypass grafting (AVR, 25%; MVR, 14%). There were 17 deaths (3.7%)
occurring during the same hospitalization or within 30 days (AVR, 10/254
[3.9%]; MVR, 7/202 [3.5%]). Follow-up is 94.5% complete and ranges from 1.0
to 131 months (mean, 55 +/- 37 months; total, 2,073 patient-years). In the
AVR group, 53 late deaths have occurred and actuarial survival is 80% +/-
3% at 5 years and 47% +/- 9% at 10 years. Twenty-one patients have
sustained thromboembolic episodes (1.8%/patient-year), and the probability
of remaining free of thromboembolism at 10 years is 67% +/- 13%. The mean
improvement in New York Heart Association functional class from
preoperative to postoperative is 3.1 +/- 0.76 to 1.6 +/- 0.84 (p <
0.0001). In the MVR group, there have been 41 late deaths, and the
actuarial survival was 80% +/- 3% at 5 years and 63% +/- 5% at 10 years.
Twenty-eight patients have sustained thromboembolic complications
(2.9%/patient-year), and the probability of remaining free of
thromboembolism at 10 years is 77% +/- 5%.(ABSTRACT TRUNCATED AT 250 WORDS)
ARTICLES
St. Jude prosthesis for aortic and mitral valve replacement: a ten-year experience
Division of Cardiothoracic Surgery, Medical University of South Carolina, Charleston 29425.
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