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Ann Thorac Surg 1993;56:387-389
© 1993 The Society of Thoracic Surgeons

Articles

Intraoperative procurement of autologous fibrin glue

Robert L. Quigley, MD, DPhil*, James A. Perkins, MD, Robert J. Gottner, MD, Ronald D. Curran, MD, Birgitta E. Kuehn, CCP, William J. Hoff, CCP, Michael E. Wallock, CCP, Carl E. Arentzen, MD, John C. Alexander, Jr, MD

Departments of Surgery and Medicine, Northwestern University, Evanston Hospital, Evanston, Illinois USA

Accepted for publication April 19, 1993.

* Address reprint requests to Dr Quigley, Cardiothoracic Division, Department of Surgery, Northwestern University, Evanston Hospital, 2650 Ridge Ave, Evanston, IL 60201.

A method of intraoperative procurement of autologous fibrin glue is described. The relative efficacy of our autologous preparation is compared with that of fibrin glue made with homologous cryoprecipitate. Experimentally, the fibrinogen content and the strength are less than those found in cryoprecipitate and appear related to the fibrinogen content of the autologous plasma used as substrate in the fibrin glue reaction. Clinically, no significant differences are noted in the performance of autologous fibrin glue. We believe the absence of the risk of blood-borne infection with the autologous product is a major advantage.




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