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The Annals of Thoracic Surgery, Vol 56, 104-107, Copyright © 1993 by The Society of Thoracic Surgeons
GW Wahl, AJ Swinburne, AJ Fedullo, DK Lee and D Shayne
To determine whether age or obstructive lung disease affects pulmonary
function changes caused by uncomplicated coronary artery bypass grafting,
we measured pulmonary function before operation and then 3 or 4 days, 7
days, and 17 +/- 2.2 weeks after operation in elderly patients (age, 74.8
+/- 3.3 years) and patients with obstructive lung disease (ratio of forced
expiratory volume in 1 second to forced vital capacity, 0.60 +/- 8.8) and
compared the results with those of a "normal" group. In all three groups a
severe restrictive defect developed on day 3 (vital capacity, 61% +/- 20%
of the preoperative value). Vital capacity recovered to 76.4% +/- 18.5% of
the preoperative value on day 7. Three months after coronary artery bypass
grafting, lung function had recovered to preoperative baseline (p >
0.2). The percent change from baseline in vital capacity, forced expiratory
volume in 1 second, total lung capacity, and diffusing capacity for carbon
monoxide was the same in all three groups throughout the study. A severe,
reversible restrictive pulmonary function change follows coronary artery
bypass grafting. This change is not affected by age or preexisting
moderately severe obstructive lung disease.
ARTICLES
Effect of age and preoperative airway obstruction on lung function after coronary artery bypass grafting
Division of Pulmonary and Critical Care Medicine, University of Rochester, Rochester General Hospital, New York 14621.
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