ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
Pierantonio A. Russo
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Greenspan, J. S.
Right arrow Articles by Shaffer, T. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Greenspan, J. S.
Right arrow Articles by Shaffer, T. H.

Ann Thorac Surg 1993;55:927-932
© 1993 The Society of Thoracic Surgeons

Articles

Operative creation of left to right cardiac shunts: Pulmonary functional sequelae

Jay S. Greenspan, MD*, Deborah A. Davis, MD, Pierantonio A. Russo, MD, Marla R. Wolfson, PhD, Thomas H. Shaffer, PhD

Thomas Jefferson University and Temple University Schools of Medicine, St. Christopher's Hospital for Children, Philadelphia, Pennsylvania USA

Accepted for publication July 22, 1992.

* Address reprint requests to Dr Greenspan, Division of Neonatology, Thomas Jefferson University Hospital, College Building, Suite 700, 1025 Walnut St, Philadelphia, PA 19107.

The creation of left to right cardiac shunts in neonates is frequently complicated by pulmonary morbidity in the immediate postoperative course. To elucidate the pattern, severity, and cause of lung dysfunction, pulmonary function testing was performed preoperatively and 1, 3, and 7 days postoperativiely on 7 neonates undergoing Blalock-Taussig shunting. Pulmonary mechanics (compliance, conductance) were determined with esophageal manometry and pneumotachography, and functional residual capacity was measured by the helium dilution technique. The infants had pulmonary function preoperatively that was similar to that of healthy term neonatal controls. Significant decreases in compliance, conductance, and functional residual capacity were found on the first postoperative day (57%, 21%, and 53% of predicted, respectively). Alterations in conductance were more severe than those in compliance, but both were low through postoperative day 3. Functional residual capacity was the least affected parameter and recovered by postoperative day 3. All parameters were normal by postoperative day 7. These data indicate that shunting is associated with pulmonary morbidity through the third postoperative day that affects the airways more than the lung parenchyma. Pulmonary function studies of these infants may clarify the etiology of pulmonary dysfunction and have an impact on therapeutic strategies used in neonates undergoing cardiac operations.




This article has been cited by other articles:


Home page
 Anesth. Analg.Home page
S. A. Stayer, L. K. Diaz, D. L. East, J. N. Gouvion, T. L. Vencill, E. D. McKenzie, C. D. Fraser, and D. B. Andropoulos
Changes in Respiratory Mechanics Among Infants Undergoing Heart Surgery
Anesth. Analg., January 1, 2004; 98(1): 49 - 55.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
D. A. Paul, J. S. Greenspan, D. A. Davis, P. Russo, and M. J. Antunes
THE ROLE OF CARDIOPULMONARY BYPASS AND SURFACTANT IN PULMONARY DECOMPENSATION AFTER SURGERY FOR CONGENITAL HEART DISEASE
J. Thorac. Cardiovasc. Surg., May 1, 1999; 117(5): 1025 - 1026.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 1993 by The Society of Thoracic Surgeons.