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Ann Thorac Surg 1993;55:543-544
© 1993 The Society of Thoracic Surgeons

Articles

Preparation of autologous fibrin glue from pericardial blood

Henrik K. Kjaergard, MD*, Ulla S. Weis-Fogh, MSc, Jens J. Thiis, MD

Department of Cardiothoracic Surgery, Rigshospitalet, and Institute for Experimental Research in Surgery, University of Copenhagen, Copenhagen, Denmark

Accepted for publication November 19, 1992.

* Address reprint requests to Dr Kjaergard, Department of Cardiothoracic Surgery, Rigshospitalet, Copenhagen, 2100, Denmark.

To salvage patients' blood and improve hemostasis in cardiac operations, autologous fibrin glue was prepared in a new way by means of ethanol from pericardial blood. The yield from 44 mL of blood was 2.1 ± 0.7 mL (mean ± standard deviation) of fibrinogen concentrate with a concentration of 25.1 ± 7.5 mg/mL; 2.7 mL of two-component glue was obtained after the addition of thrombin solution. The glue has the advantages of safety from transmission of viral diseases and from immunologic reactions.




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