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The Annals of Thoracic Surgery, Vol 55, 543-544, Copyright © 1993 by The Society of Thoracic Surgeons
HK Kjaergard, US Weis-Fogh and JJ Thiis
To salvage patients' blood and improve hemostasis in cardiac operations,
autologous fibrin glue was prepared in a new way by means of ethanol from
pericardial blood. The yield from 44 mL of blood was 2.1 +/- 0.7 mL (mean
+/- standard deviation) of fibrinogen concentrate with a concentration of
25.1 +/- 7.5 mg/mL; 2.7 mL of two-component glue was obtained after the
addition of thrombin solution. The glue has the advantages of safety from
transmission of viral diseases and from immunologic reactions.
ARTICLES
Preparation of autologous fibrin glue from pericardial blood
Department of Cardiothoracic Surgery, Rigshospitalet, Copenhagen, Denmark.
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