ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Janzing, H. M.
Right arrow Articles by Rosseel, M. T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Janzing, H. M.
Right arrow Articles by Rosseel, M. T.

The Annals of Thoracic Surgery, Vol 55, 368-371, Copyright © 1993 by The Society of Thoracic Surgeons

ARTICLES

Intrapleural quinacrine instillation for recurrent pneumothorax or persistent air leak

HM Janzing, A Derom, E Derom, C Eeckhout, F Derom and MT Rosseel
Surgical Department, University Hospital, Ghent, Belgium.

From 1982 to 1990, 27 patients with recurrent pneumothorax or persistent air leak (28 episodes) underwent pleurodesis with intrapleural administration of quinacrine, according to a standardized scheme. A first evaluation was done about 1 month after the intervention. In August 1990, all patients were invited for a second check-up. In 4 patients quinacrine plasma concentrations were determined. There was one early failure. No late recurrences were observed. Neither serious nor late complications were seen with our low- dose regimen. Transient fever was the only constant side effect. In contrast to other chemicals proposed for pleurodesis, quinacrine did not cause major pain. Only very low quinacrine plasma concentrations (peak, < 10 ng/mL) were found. In conclusion, chemical pleurodesis with quinacrine can be considered a safe and effective treatment. The number of administrations as well as the dosage are important to prevent morbidity and recurrence.


This article has been cited by other articles:


Home page
 J. Thorac. Cardiovasc. Surg.Home page
C. Andreetti, F. Venuta, M. Anile, T. De Giacomo, D. Diso, M. Di Stasio, E. A. Rendina, and G. F. Coloni
Pleurodesis with an autologous blood patch to prevent persistent air leaks after lobectomy
J. Thorac. Cardiovasc. Surg., March 1, 2007; 133(3): 759 - 762.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 1993 by The Society of Thoracic Surgeons.