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Ann Thorac Surg 1993;55:86-88
© 1993 The Society of Thoracic Surgeons

Articles

Prophylactic digitalization fails to control dysrhythmia in thoracic esophageal operations

Andrew J. Ritchie, FRCSEd*, Michael Tolan, FRCSI, Michael Whiteside, FRCSI, James A. McGuigan, FRCS, John R.P. Gibbons, FRCS

Northern Ireland Regional Thoracic Surgical Department, Royal Victoria Hospital, Belfast, Northern Ireland, United Kingdom

Accepted for publication April 20, 1992.

* Address reprint requests to Mr Ritchie, Northern Ireland Regional Thoracic Surgical Department, Royal Victoria Hospital, Belfast BT12 6BA, Northern Ireland, UK.

A prospective, controlled, randomized study of 80 patients undergoing esophageal operations was undertaken, in which one group of patients was given digoxin and the other was not. The incidence of cardiac dysrhythmia was compared in each group. Twenty-six patients underwent operation for benign disease. Equal numbers were digitalized or not and no dysrhythmias occurred. Fifty-four patients underwent operation for malignant disease. Of 26 in the group digitalized, 12 suffered dysrhythmia (46%). Of 28 not digitalized, 9 suffered dysrhythmia (32%). Overall, 39% of patients with malignant disease suffered a dysrhythmia compared with none with benign disease (p < 0.002 by {chi} 2).




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