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The Annals of Thoracic Surgery, Vol 55, 310-313, Copyright © 1993 by The Society of Thoracic Surgeons

ARTICLES

Pharmacological bridge to cardiac transplantation: current limitations

DY Loisance, PH Deleuze, R Houel, C Benvenuti, A el Sayed, JP Mazzucotelli, A Tarral, JP Saal and JP Cachera
Centre de Recherches Chirurgicales, CHU Henri Mondor, Faculte de Medicine, Creteil, France.

Addition of intravenous enoximone to sympathomimetic agents permits a rapid and drastic improvement in the clinical and hemodynamical condition of patients in cardiogenic shock referred for a mechanical bridge to transplantation. The present experience, based on the management of 52 patients, permits us to point out the current limitations of this pharmacological bridge: the rate of sudden death, the incompleteness of the physical rehabilitation of the patients, and the vanishing effect of intravenous enoximone.


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