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The Annals of Thoracic Surgery, Vol 54, 898-901, Copyright © 1992 by The Society of Thoracic Surgeons

ARTICLES

Role of open lung biopsy in diagnosing pulmonary complications of AIDS

GD Trachiotis, GH Hafner, WR Hix and BL Aaron
Division of Cardiothoracic Surgery, George Washington University Medical Center, Washington, DC 20037.

Over a 4-year period, 25 patients with pulmonary complications of acquired immunodeficiency syndrome underwent open lung biopsy for diagnosis. Results of the biopsy led to a change in therapy in 15, and of this group, 8 patients improved clinically and were discharged. We believe that a select group of acquired immunodeficiency syndrome patients with pulmonary disease will benefit from open lung biopsy. Our indications for open lung biopsy are (1) a nondiagnostic bronchoscopy, (2) failed medical therapy after a diagnostic bronchoscopy, (3) failed empiric medical therapy after a nondiagnostic bronchoscopy or after a second nondiagnostic bronchoscopy, and (4) when any of the forementioned are accompanied with a worsening chest roentgenogram. Patients with acquired immunodeficiency syndrome who have a deteriorating respiratory status or require mechanical ventilation should not undergo open lung biopsy.

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