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The Annals of Thoracic Surgery, Vol 54, 150-151, Copyright © 1992 by The Society of Thoracic Surgeons
DR Jobes, SC Nicolson, JM Steven, M Miller, ML Jacobs and WI Norwood Jr
Circulatory and metabolic homeostasis in patients with hypoplastic left
heart syndrome is dependent on a delicate balance between systemic and
pulmonary blood flow. Hypocarbia can result in a marked decrease in
pulmonary vascular resistance accompanied by pulmonary overcirculation,
systemic hypotension, metabolic acidosis, and death. This report
illustrates that early and precise control of the arterial carbon dioxide
tension using inspired carbon dioxide can be effective in preventing or
treating instability arising during management of a patient with
hypoplastic left heart syndrome.
ARTICLES
Carbon dioxide prevents pulmonary overcirculation in hypoplastic left heart syndrome
Children's Hospital of Philadelphia, Pennsylvania.
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