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Ann Thorac Surg 1992;53:957-964
© 1992 The Society of Thoracic Surgeons
Division of Cardiothoracic Surgery, The New York Hospital-Cornell Medical Center, New York, New York USA
* Address reprint requests to Dr Krieger, Division of Cardiac Surgery, Room F2108, The New York Hospital-Cornell Medical Center, 525 East 68th St, New York, NY 10021 USA.
Eleven dogs were subjected to a 150-minute period of cardiopulmonary bypass that consisted of a high-flow, normothermic phase, a high-flow, hypothermic phase, a low-flow, hypothermie phase, and then a high-flow, rewarming phase. Regional blood flow and oxygen consumption to the brain, intestines, kidney, and hind limb were determined at baseline and at 10-minute intervals during Cardiopulmonary bypass. Blood flow to the carotid artery, superior mesenteric artery, and renal artery declined significantly with hypothermic cardiopulmonary bypass whereas blood flow to the femoral artery increased significantly. Although total body oxygen consumption returned to baseline values at the end of the rewarming phase, oxygen consumption for these regions differed somewhat from their baseline values. We conclude that blood flow during hypothermic cardiopulmonary bypass is shunted to skeletal muscle, particularly with high pump flows. Additionally, the return of total body oxygen consumption to baseline after rewarming is not necessarily reflected at the regional level.
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