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Ann Thorac Surg 1992;53:338-340
© 1992 The Society of Thoracic Surgeons


Articles

Systemic recombinant tissue plasminogen activator lysis for left atrial thrombus formation after single-lung retransplantation

Christof Schmid, MD*,a,b,c, Dietrich Christoph Gulba, MDa,b,c, Bernd Heublein, MDa,b,c, Josef Kemnitz, MD, PhDa,b,c, Axel Haverich, MDa,b,c

a Division of Thoracic and Cardiovascular Surgery, Surgical Center, Hannover, Germany
b Division of Cardiology, Medical Center, Hannover, Germany
c Institute of Pathology, Medizinische Hochschule Hannover, Hannover, Germany

Accepted for publication July 25, 1991.

* Address reprint requests to Dr. Schmid, Klinik für Thorax-, Herz- und Gefäβchirurgie, Zentrum Chirurgie, Medizinische Hochschule Hannover, Konstanty-Gustchow-Str 8, D-300 Hannover 61, Germany.

This report describes a recipient of single-lung transplantation surviving extraordinary complications: (1) early graft failure mandating retransplantation; (2) left atrial thrombus formation, which resolved by recombinant tissue plasminogen activator lysis; (3) and development of a "locked-in-syndrome." Possible underlying mechanisms are discussed.




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