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Ann Thorac Surg 1992;53:326-327
© 1992 The Society of Thoracic Surgeons

Articles

Cyclosporine-associated central neurotoxicity after heart transplantation

Robert P. McManus, MD*, Daniel P. O'Hair, MD, Jan Schweiger, RN, MSN, Jan Beitzinger, RN, BSN, Ronald Siegel, MD

Departments of Cardiothoracic Surgery and Cardiology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA

Accepted for publication July 16, 1991.

* Address reprint requests to Dr McManus, Department of Cardiothoracic Surgery, Medical College of Wisconsin, 8700 West Wisconsin Ave, Milwaukee, WI 53226.

Cyclosporine central neurotoxicity has been described after bone marrow, kidney, and liver transplantation but has not been well documented after heart transplantation. This case illustrates severe reversible neurotoxicity after heart transplantation with characteristic radiographic changes in magnetic resonance imaging.




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