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Ann Thorac Surg 1991;52:1354-1367
© 1991 The Society of Thoracic Surgeons
The Heart Institute, Long Island Jewish Medical Center, New Hyde Park, New York USA
* Address reprint requests to Dr Barner, The Heart Institute, Rm 2123, Long Island Jewish Medical Center, New Hyde Park, NY 11042 USA.
The Oxford International Symposium on myocardial preservation provided an appropriate milestone and impetus to survey one aspect of operative myocardial preservation, namely blood cardioplegia, and to contrast it with the more popular crystalloid cardioplegia. This review is by no means complete or exhaustive but represents my best effort to summarize important information that has accumulated in the literature as blood cardioplegia, and our understanding of it, has evolved. It is appropriate to compare blood and crystalloid cardioplegia with respect to biochemical and physiological differences. Clinical comparison has been limited, for the most part, to randomized studies, and a number of differences and details of clinical management of the two techniques have been omitted, either because they seemed unimportant or there was no good information that would allow an objective comparison of their significance. Hopefully, the reader will recognize the intent to focus on meaningful differences and similarities between the two techniques and to present them fairly.
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S. Chocron, K. Alwan, Y. Yan, G. Toubin, D. Kaili, T. Anguenot, L. Latini, F. Clement, J.-F. Viel, and J.-P. Etievent Warm reperfusion and myocardial protection Ann. Thorac. Surg., December 1, 1998; 66(6): 2003 - 2007. [Abstract] [Full Text] [PDF]
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J. S. Lawton, P.-W. Hsia, and R. J. Damiano Jr The adenosine-triphosphate-sensitive potassium-channel opener pinacidil is effective in blood cardioplegia Ann. Thorac. Surg., September 1, 1998; 66(3): 768 - 773. [Abstract] [Full Text] [PDF]
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G. Li, J. A. Sullivan, J. M. You, and R. I. Hall Effect of Pressure on Myocardial Function After 6-Hour Preservation With Blood Cardioplegia Ann. Thorac. Surg., January 1, 1998; 65(1): 115 - 124. [Abstract] [Full Text] [PDF]
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J. R. Handy Jr., B. H. Dorman, M. J. Cavallo, R. B. Hinton, R. C. Roy, F. A. Crawford, and F. G. Spinale DIRECT EFFECTS OF OXYGENATED CRYSTALLOID OR BLOOD CARDIOPLEGIA ON ISOLATED MYOCYTE CONTRACTILE FUNCTION J. Thorac. Cardiovasc. Surg., October 1, 1996; 112(4): 1064 - 1072. [Abstract] [Full Text]
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J. S. Lawton, J. D. Sepic, C. T. Allen, P.-W. Hsia, and R. J. Damiano Jr Myocardial Protection With Potassium-Channel Openers Is as Effective as St. Thomas' Solution in the Rabbit Heart Ann. Thorac. Surg., July 1, 1996; 62(1): 31 - 38. [Abstract] [Full Text]
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S. L. Maskal, N. M. Cohen, P.-W. Hsia, A. S. Wechsler, and R. J. Damiano Jr. HYPERPOLARIZED CARDIAC ARREST WITH A POTASSIUM-CHANNEL OPENER, APRIKALIM J. Thorac. Cardiovasc. Surg., October 1, 1995; 110(4): 1083 - 1095. [Abstract] [Full Text]
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J. R. Handy, F. G. Spinale, R. Mukherjee, and F. A. Crawford Hypothermic potassium cardioplegia impairs myocyte recovery of contractility and inotropy J. Thorac. Cardiovasc. Surg., April 1, 1994; 107(4): 1050 - 1058. [Abstract] [Full Text]
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