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Kenji Kusuhara
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Ann Thorac Surg 1991;52:1158-1160
© 1991 The Society of Thoracic Surgeons

Articles

Propranolol for intractable hemolysis after open heart operation

Yutaka Okita, MD*, Shigehito Miki, MD, Kenji Kusuhara, MD, Yuichi Ueda, MD, Takafumi Tahata, MD, Kazuo Yamanaka, MD

Department of Cardiovascular Surgery, Tenri Hospital, Tenri, Japan

Accepted for publication March 25, 1991.

* Address reprint requests to Dr Okita, Department of Cardiovascular Surgery, Tenri Hospital, 200 Mishima, Tenri, Nara 632, Japan.

Postoperative intravascular hemolysis occurring in 2 patients was alleviated by propranolol. One patient underwent mitral valve replacement and had development of intractable hemolysis due to a paravalvular leak. The other patient underwent ventricular septal defect closure and had hemolysis caused by the Dacron patch. Both patients were given oral propranolol, and the degree of hemolysis decreased substantially. Although the exact mechanism of the propranolol effect on mechanical intravascular hemolysis is unclear, propranolol is thought to reduce the shearing stress between erythrocytes and the foreign material by slowing the velocity of the circulation.




This article has been cited by other articles:


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Benefits of a {beta}-Blocker for Intractable Hemolysis due to Paraprosthetic Leakage
Asian Cardiovasc Thorac Ann, October 1, 2007; 15(5): 441 - 443.
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 Ann. Thorac. Surg.Home page
Y. Okita and S. Miki
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Ann. Thorac. Surg., December 1, 1992; 54(6): 1247 - 1247.
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 Ann. Thorac. Surg.Home page
A. Golino, P. Stassano, and N. Spampinato
Hemolysis after open heart operations
Ann. Thorac. Surg., December 1, 1992; 54(6): 1246 - 1247.
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