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The Annals of Thoracic Surgery, Vol 52, 1076-1082, Copyright © 1991 by The Society of Thoracic Surgeons
SY DeLeon, MN Ilbawi, WR Wilson Jr, RA Arcilla, OG Thilenius, S Bharati, M Lev and FS Idriss
Over a 15-year period, 12 patients with endocardial cushion defects
undergoing correction had subaortic stenosis requiring operative
intervention. Ages ranged from 4 months to 17 years (mean, 7 +/- 6 years)
and subaortic gradients from 15 to 100 mm Hg (mean, 60 +/- 25 mm Hg).
Subaortic stenosis was due to discrete fibromuscular tissues in 7 patients,
mitral valve malattachment in 3, and tunnel outflow in 2. In 2, the
subaortic stenosis was clinically significant at the time of endocardial
cushion defects repair, whereas in 10 it was noted 2 to 14 years
postoperatively (mean, 6.3 +/- 5 years). Surgical relief of subaortic
stenosis was accomplished by resection of muscle tissues in 7, apicoaortic
conduit insertion in 2, modified Konno procedure (aortic valve preserved)
in 2, and lifting of malattached mitral valve from the outflow in 1. There
was no early death and one late death (infected conduit). Severe mitral
insufficiency developed in the patient who had the mitral valve lifted and
necessitated valve replacement. Postoperative echocardiographic gradient in
9 patients ranged from 0 to 36 mm Hg (mean, 10.5 +/- 14 mm Hg). Clinically
significant subaortic stenosis has not developed in any patient in 15 years
of follow-up (mean, 5 +/- 4 years). We conclude that in subaortic stenosis
associated with endocardial cushion defects, resection is effective for
discrete obstruction, whereas a modified Konno procedure is preferable for
obstruction due to tunnel outflow or mitral valve malattachment.
ARTICLES
Surgical options in subaortic stenosis associated with endocardial cushion defects
Heart Institute for Children, Christ Hospital and Medical Center, Oak Lawn, Illinois.
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