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Ann Thorac Surg 1991;52:325-327
© 1991 The Society of Thoracic Surgeons
a Divisions of Cardiothoracic Surgery and Gastroenterology, University of Missouri School of Medicine, Columbia, Missouri, USA
b Department of Surgery, The University of Texas, Southwestern Medical School, Dallas, Texas, USA
* Address reprint requests to Dr Landreneau, Section of Thoracic Surgery, University of Pittsburgh, Montefiore Uuiversity Hospital, 3459 Fifth Ave, Pittsburgh, PA 15213.
Twenty-seven patients with advanced gastroesophageal reflux disease have been treated with combined transthoracic parietal cell vagotomy and Collis-Nissen fundoplication. Gastric acid analyses (n = 20) obtained preoperatively and 6 months postoperatively demonstrated a significant late reduction in gastric acid output. Twenty-six patients (96%) have experienced relief of gastroesophageal reflux disease at a mean of 13.3 months (range, 6 to 25 months) without postvagotomy symptoms. Transthoracic parietal cell vagotomy may be considered as an adjunct to mechanical surgical control of advanced gastroesophageal reflux disease.
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