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Ann Thorac Surg 1991;52:236-243
© 1991 The Society of Thoracic Surgeons
Department of Thoracic and Cardiovascular Surgery, Sapporo Medical College and Hospital, Sapporo, Japan
Accepted for publication February 27, 1991.
* Address reprint requests to Dr Kazui, Department of Thoracic and Cardiovascular Surgery, Sapporo Medical College and Hospital, South 1, West 16, Chuoku, Sapporo 060, Japan.
Clinical results achieved in 100 cases of aortic valve replacement with the Omniscience (O-S) valve during the period from 1980 to 1985 as well as 100 cases of aortic valve replacement with the Cmnicarbon (O-C) valve during the period from 1985 to 1989 were studied. Concomitant surgical procedures including mitral valve replacement were performed in 63 patients in the O-S group and 67 patients in the O-C group. Cumulative follow-up in the two groups was carried out for a total of 559 and 273 patient-years, respectively. The overall 4-year actuarial survival rate was 82% ± 3.8% in the O-S group and 89.5% ± 3.2% in the O-C group, the corresponding rates for patients undergoing isolated aortic valve replacement being 82.9% ± 4.2% in the O-S group and 91.9% ± 3.5% in the O-C group. The overall 4-year actuarial event-free rate with respect to thromboembolic complications was 88.8% ± 3.3% in the O-S group and 94.4% ± 2.8% in the O-C group, as compared with the corresponding rates of 89.2% ± 3.6% in the O-S group and 95.9% ± 2.8% in the O-C group for patients undergoing isolated aortic valve replacement. The overall rate of valve-related complications, including thromboembolism, anticoagulant-related hemorrhage, perivalvular leak, infection, and structural failure, was 78.8% ± 4.2% in the O-S group and 89.3% ± 3.5% in the O-C group (p < 0.05), and for isolated aortic valve replacement, 79.7% ± 4.5% in the O-S group and 89.6% ± 4.1% in the O-C group. The data for the two groups were nonhomogeneous and the periods concerned were not concurrent, thus precluding strict comparison; nevertheless, medium-term follow-up in the O-C group indicated satisfactory clinical results.
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