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The Annals of Thoracic Surgery, Vol 51, 733-738, Copyright © 1991 by The Society of Thoracic Surgeons
GK Sethi, JG Copeland, T Moritz, W Henderson, K Zadina and S Goldman
Considerable controversy exists regarding relative morbidity associated
with the saphenous vein graft (SVG) and internal mammary artery (IMA) graft
in patients undergoing myocardial revascularization. As a part of the
cooperative study on use of antiplatelet drugs for graft patency, operative
and postoperative data were prospectively collected on 1,150 patients who
underwent either SVG (n = 656) or IMA anastomosis (n = 494) to the left
anterior descending coronary artery. There were no differences in baseline
characteristics of patients, distribution of randomization among treatment
groups, and total number of distal anastomoses performed between the two
groups. The aortic cross-clamp time, cardiopulmonary bypass duration,
operative time, and chest tube drainage were greater (p = 0.0001) in the
patients with IMA grafts compared with SVG. However, there was no
difference in the operative mortality rate, the amount of blood and blood
products received, the reoperation rate for control of postoperative
bleeding, and incidence of wound complications between the two groups. The
early and 1-year patency rates for the IMA were slightly but not
significantly better than the SVG patency rates (92.8% versus 90.1% for
1-year patency; p = 0.309). In conclusion, use of IMA is associated with a
longer operative time as well as increased postoperative bleeding compared
with the SVG. It, however, does not increase operative mortality or
postoperative morbidity.
ARTICLES
Comparison of postoperative complications between saphenous vein and IMA grafts to left anterior descending coronary artery
Division of Cardiothoracic Surgery, Department of Veterans Affairs Medical Center, Tucson, AZ 85723.
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