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Ann Thorac Surg 1991;51:335-340
© 1991 The Society of Thoracic Surgeons
McGill University Lung Transplant Program and The Montreal General Hospital, Montreal, Quebec, Canada
* Address reprint requests to Dr Shennib, McGill University Lung Transplantation Program, The Montreal General Hospital, 1650 Cedar Avenue, Room 9827 LH, Montreal, Que, Canada H3G 1A4.
One of the dilemmas in the management of lung allotransplant recipients is our inability to precisely determine the cause of graft dysfunction. Differentiating between lung allograft infection, rejection, atelectasis, or ischemic injury remains a difficult task. Tests directed at identifying systemic abnormalities such as peripheral blood analysis so far have been nonspecific and unlikely to accurately and promptly represent changes occurring within the lungs. Transbronchial biopsy and bronchoalveolar lavage have emerged as two methods with the most potential for aiding in the establishment of diagnosis. This review attempts to provide the readers with a current knowledge of the cellular events in lung aliograf t and the status of bronchoalveolar lavage in experimental and clinical lung transplantation.
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