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The Annals of Thoracic Surgery, Vol 51, 253-261, Copyright © 1991 by The Society of Thoracic Surgeons
Y Watanabe, J Shimizu, M Oda, Y Hayashi, S Watanabe, Y Tatsuzawa, T Iwa, M Suzuki and T Takashima
An aggressive attitude toward surgical treatment was taken in patients with
N2 non-small cell lung cancer in the past 10 years. Computed tomographic
scanning was employed in the diagnosis of N2 disease, and had a
true-positive rate of 57%. Among patients with N2 disease detected by
computed tomographic scanning, surgical intervention was attempted except
for those with unresectable disease. Of 190 patients with clinical N2
disease, 115 underwent surgical exploration: 9 patients had only an
exploratory thoracotomy, 53 patients underwent a curative operation, and 53
had a noncurative operation. The overall 5- year survival rate of these
patients was 16% and that of curatively resected patients was 20%. There
were 47 patients whose N2 disease was not recognized before operation. The
5-year survival rate of this group was 20% overall and 33% in curatively
resected cases. The overall 5- year survival rate of patients with N2
disease who underwent resection (106 with clinical N2 disease and 47 with
clinically unrecognized N2 disease) was 17%, and that of the 84 patients
undergoing curative operations was 24%. An aggressive attitude toward
surgical intervention can be advocated for patients with N2 disease on the
basis of our present results.
ARTICLES
Aggressive surgical intervention in N2 non-small cell cancer of the lung
Department of Surgery, Kanazawa University School of Medicine, Japan.
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