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Ann Thorac Surg 1991;51:242-244
© 1991 The Society of Thoracic Surgeons

Articles

Intrathoracic fibrin glue for postoperative pleuropulmonary fistula

Yuji Yasuda, MD*, Atsumi Mori, MD, Hirofumi Kato, MD, Shozo Fujino, MD, Shoji Asakura, MD

The Second Department of Surgery, Shiga University of Medical Science, Otsu, Japan

Accepted for publication October 16, 1990.

* Address reprint requests to Dr Yasuda, The Second Department of Surgery, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga 520-21, Japan.

Twenty cases of persistent pleuropulmonary fistula after a thoracic surgical procedure were successfully treated with fibrin glue injection into the thoracic cavity through a drainage tube. A new technique, the overlying method, which is a modification of the conventional technique of fibrin glue injection, was devised. Each patient received one to four injections (mean number, 1.6). This method resulted in closure of the pleuropulmonary fistula in all but 1 patient. Minor complications included pain in 1 patient and fever in 3 patients. A control study involving 24 patients with pleuropulmonary fistula was performed. Autoblood, OK-432, and tetracycline were used instead of fibrin glue. The fistula resolved in 12 patients. Complications after injection included pain in 15 patients, fever in 10, and occlusion of the chest tube in 4. With our new method, patients rarely exhibited pain and fever, and occlusion of the chest tube did not occur.




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R. B. Ponn, R. S. D'Agostino, H. Stern, and J. L. Westcott
Treatment of peripheral bronchopleural fistulas with endobronchial occlusion coils
Ann. Thorac. Surg., December 1, 1993; 56(6): 000349759390679C - 349759390679C.
[Abstract] [PDF]


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