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Maurizio Merlo
Federico Brunelli
Pietro A. Abbruzzese
Giancarlo Crupi
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Ann Thorac Surg 1991;51:227-231
© 1991 The Society of Thoracic Surgeons


Articles

Long-term results after atrial correction of complete transposition of the great arteries

Maurizio Merlo, MD*,a,b, S.Mario De Tommasi, MDa,b, Federico Brunelli, MDa,b, Pietro A. Abbruzzese, MDa,b, Giancarlo Crupi, MDa,b, Italo Ghidoni, MDa,b, Angelo Casari, MDa,b, Antonio Pitì, MDa,b, Filippo Mamprin, MDa,b, Lucio Parenzan, MDa,b

a Divisions of Cardiac Surgery and Cardiology, Ospedali Riuniti di Bergamo, Bergamo, Italy
b Division of Cardiac Surgery, Ospedale S. Michele, Cagliari, Italy

Accepted for publication October 10, 1990.

* Address reprint requests to Dr Merlo, Divisione di Cardiochirurgia, Ospedali Riuniti di Bergamo, Largo Barozzi 1, 24100 Bergamo, Italia.

This study presents the late results for the first 104 consecutive patients surviving an atrial repair for transposition of the great arteries (TGA) between January 1971 and December 1978 (group 1). Mean follow-up was 12 years (range, 0.1 to 17.7 years). The actuarial survival rate at 18 years was 84.2% (70% confidence limits, 79% to 88%) for simple TGA and 93.7% (70% confidence limits, 84% to 97%) for complex TGA. Nine of the 11 deaths were sudden. Two (2.6%) of the 78 late survivors operated on for simple TGA are in New York Heart Association functional class III or IV versus 4 (26.7%) of the 15 survivors with complex TGA; the other patients are doing very well. To better assess long-term results, we report the findings for randomly obtained electrocardiograms, Holter monitor recordings, radionuclide angiographic studies, and cardiac catheterizations performed in 1987 in a larger group of 159 long-term survivors of atrial repair operated on at Ospedale Riuniti di Bergamo from January 1971 to December 1984 (group 2), which includes all of group 1. The findings confirm that the arterial switch repair is the procedure of choke for complex TGA and that there is a major incidence (approximately 10%) of systemic right ventricular dysfunction and rhythm disturbances after the atrial repair. On the other hand, our late survival rate at 18 years of 84% for simple TGA with 97.5% of the patients in functional class I is a result that should be kept in mind, especially in institutions where the arterial switch is a relatively new approach and presumably it a higher risk to cause early death.




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