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Ann Thorac Surg 1990;50:946-948
© 1990 The Society of Thoracic Surgeons
a Department of Thoracic and Cardiovascular Surgery Helsinki University Central Hospital, Helsinki, Finland
b Department of Pediatric Pathology, Helsinki University Central Hospital, Helsinki, Finland
Accepted for publication August 13, 1990.
* Address reprint requests to Dr Heikkinen, Department of Thoracic and Cardiovascular Surgery, Helsinki University Central Hospital, Haartmaninkatu 4, SF-00290 Helsinki, Finland.
Repair of coarctation of the aorta by synthetic patch grafting has been complicated by late aneurysm formation. These aneurysms differ macroscopically from atherosclerotic thoracic aortic dilatations. Specimens for microscopic examination were taken from 14 of 20 patients undergoing aneurysm resection. Histological analysis of the specimens showed medionecrosis in 13 patients (93%), foreign body reaction in 11 patients (78%), and intimal thickening in 3 patients (21%). The three layers of the aortic wall could be identified in the aneurysms. On the basis of these results, we discuss the etiologic factors and pathogenetic mechanisms involved in the development of these aneurysms.
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