ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
 QUICK SEARCH:   [advanced]


     


This Article
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Goodnough, L. T.
Right arrow Articles by Silberstein, L. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Goodnough, L. T.
Right arrow Articles by Silberstein, L. E.

The Annals of Thoracic Surgery, Vol 50, 675-683, Copyright © 1990 by The Society of Thoracic Surgeons


ARTICLES

Guidelines for transfusion support in patients undergoing coronary artery bypass grafting. Transfusion Practices Committee of the American Association of Blood Banks

LT Goodnough, MF Johnston, G Ramsey, MH Sayers, RS Eisenstadt, KC Anderson, RC Rutman and LE Silberstein
Case Western Reserve University, Cleveland, OH.

We have reviewed the impact of evolving issues in coronary artery bypass grafting (CABG) on transfusion support for these patients. Issues include increased awareness of transfusion risks, reappraisal of traditional indicators triggering transfusion, and evolving alternatives to homologous blood transfusion such as autologous blood and pharmacologic therapy. These issues have been prompted by programs, such as the National Institutes of Health Consensus Conferences, to provide physicians with guidelines for appropriate use of blood components. However, evidence suggests that transfusion practice in coronary artery bypass grafting procedures remains variable and does not take into account the results of recently published clinical studies. We have therefore developed guidelines and recommendations for transfusion support in patients undergoing coronary artery bypass grafting. In summary, they are the following. 1. Institutions with coronary artery bypass grafting programs should establish a multidisciplinary approach to use a combination of interventions designed to minimize homologous blood exposure. 2. Prophylactic transfusion of plasma and platelets are of no benefit and therefore carry an unnecessary risk to the patient. 3. Special request products such as designated blood donation from first-degree relatives should not be used because of the risk of transfusion-associated graft versus host disease. 4. For support of intravascular volume, crystalloids or colloids should be used because they do not have the potential to transmit infection.


This article has been cited by other articles:


Home page
ICVTSHome page
J. J. Andreasen, M. Westen, P. A. Pallesen, S. Jensen, A. Gorst-Rasmussen, and S. P. Johnsen
Transfusion practice in coronary artery bypass surgery in Denmark: a multicenter audit
Interactive CardioVascular and Thoracic Surgery, October 1, 2007; 6(5): 623 - 627.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
The Society of Thoracic Surgeons Blood Conservatio, V. A. Ferraris, S. P. Ferraris, S. P. Saha, E. A. Hessel II, C. K. Haan, B. D. Royston, C. R. Bridges, R. S.D. Higgins, G. Despotis, et al.
Perioperative Blood Transfusion and Blood Conservation in Cardiac Surgery: The Society of Thoracic Surgeons and The Society of Cardiovascular Anesthesiologists Clinical Practice Guideline
Ann. Thorac. Surg., May 1, 2007; 83(5_Supplement): S27 - S86.
[Abstract] [Full Text] [PDF]


Home page
Anesth. Analg.Home page
B. H. Scott, F. C. Seifert, P. S. A. Glass, and R. Grimson
Blood Use in Patients Undergoing Coronary Artery Bypass Surgery: Impact Of Cardiopulmonary Bypass Pump, Hematocrit, Gender, Age, and Body Weight
Anesth. Analg., October 1, 2003; 97(4): 958 - 963.
[Abstract] [Full Text] [PDF]


Home page
SEMIN CARDIOTHORAC VASC ANESTHHome page
J. M. Karski and J. T. Balatbat
Blood Conservation Strategies in Cardiac Surgery
Seminars in Cardiothoracic and Vascular Anesthesia, June 1, 2003; 7(2): 175 - 188.
[Abstract] [PDF]


Home page
Anesth. Analg.Home page
A. M.-H. Ho, A. Lee, E. Ling, A. Daly, K. Teoh, and T. E. Warkentin
Agreements Between the Prothrombin Times of Blood Treated In Vitro with Heparinase During Cardiopulmonary Bypass (CPB) and Blood Sampled After CPB and Systemic Protamine
Anesth. Analg., January 1, 2003; 96(1): 15 - 20.
[Abstract] [Full Text] [PDF]


Home page
Br J AnaesthHome page
F. Forestier, A. Coiffic, C. Mouton, D. Ekouevi, G. Chene, and G. Janvier
Platelet function point-of-care tests in post-bypass cardiac surgery: are they relevant?
Br. J. Anaesth., November 1, 2002; 89(5): 715 - 721.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
N. Ellison
Red blood cells: an analysis of risk versus benefit
Ann. Thorac. Surg., November 1, 2001; 72(5): S1806 - 1807.
[Abstract] [Full Text] [PDF]


Home page
SEMIN CARDIOTHORAC VASC ANESTHHome page
K. Kottke-Marchant and S. Sapatnekar
Hemostatic Abnormalities in Cardiopulmonary Bypass: Pathophysiologic and Transfusion Considerations
Seminars in Cardiothoracic and Vascular Anesthesia, September 1, 2001; 5(3): 187 - 206.
[Abstract] [PDF]


Home page
SEMIN CARDIOTHORAC VASC ANESTHHome page
N. J. Skubas and G. J. Despotis
Optimal Management of Bleeding Complications After Cardiac Surgery
Seminars in Cardiothoracic and Vascular Anesthesia, September 1, 2001; 5(3): 217 - 228.
[Abstract] [PDF]


Home page
Ann. Thorac. Surg.Home page
W. C. Oliver Jr, P. J. Santrach, G. K. Danielson, G. A. Nuttall, D. R. Schroeder, and M. H. Ereth
Desmopressin does not reduce bleeding and transfusion requirements in congenital heart operations
Ann. Thorac. Surg., December 1, 2000; 70(6): 1923 - 1930.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
G. J. Despotis and L. T. Goodnough
Management approaches to platelet-related microvascular bleeding in cardiothoracic surgery
Ann. Thorac. Surg., August 1, 2000; 70(2): S20 - 32.
[Abstract] [Full Text] [PDF]


Home page
CLIN APPL THROMB HEMOSTHome page
R. Speck, D. Bonderman, L. Cook, and J. Larison
Proposed Procedure for Evaluating Platelet Concentrate Units to Be Used for Transfusion
Clinical and Applied Thrombosis/Hemostasis, July 1, 1998; 4(3): 217 - 219.
[Abstract] [PDF]


Home page
Arch Intern MedHome page
M. A. Forgie, P. S. Wells, A. Laupacis, D. Fergusson, and for the International Study of Perioperative Trans
Preoperative Autologous Donation Decreases Allogeneic Transfusion but Increases Exposure to All Red Blood Cell Transfusion: Results of a Meta-analysis
Arch Intern Med, March 23, 1998; 158(6): 610 - 616.
[Abstract] [Full Text] [PDF]


Home page
Clin. Chem.Home page
G. J. Despotis, J. H. Joist, and L. T. Goodnough
Monitoring of hemostasis in cardiac surgical patients: impact of point-of-care testing on blood loss and transfusion outcomes
Clin. Chem., September 1, 1997; 43(9): 1684 - 1696.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
H. Schmidt, P. E. Mortensen, S. L. Folsgaard, and E. A. Jensen
Autotransfusion After Coronary Artery Bypass Grafting Halves the Number of Patients Needing Blood Transfusion
Ann. Thorac. Surg., April 1, 1996; 61(4): 1177 - 1181.
[Abstract] [Full Text]


Home page
Ann. Thorac. Surg.Home page
O. Gil, J. C. Catala, A. L. Fernandez, J. A. Montero, D. Luna, O. Tovar, M. Tonz, T. Mihaljevic, L. K. von Segesser, and M. I. Turina
Normothermia, Hypothermia, and Postoperative Bleeding
Ann. Thorac. Surg., October 1, 1995; 60(4): 1160 - 1161.
[Full Text]


Home page
Ann. Thorac. Surg.Home page
L. T. Goodnough, G. J. Despotis, C. W. Hogue Jr, and T. B. Ferguson Jr
On the Need for Improved Transfusion Indicators in Cardiac Surgery
Ann. Thorac. Surg., August 1, 1995; 60(2): 473 - 480.
[Abstract] [Full Text]


Home page
Ann. Thorac. Surg.Home page
L. Sandrelli, A. Pardini, R. Lorusso, M. L. Sala, M. Licenziati, and O. Alfieri
Impact of Autologous Blood Predonation on a Comprehensive Blood Conservation Program
Ann. Thorac. Surg., March 1, 1995; 59(3): 730 - 735.
[Abstract] [Full Text]


Home page
J. Thorac. Cardiovasc. Surg.Home page
G. J. Despotis, S. A. Santoro, E. Spitznagel, K. M. Kater, J. L. Cox, P. Barnes, and D. G. Lappas
Prospective evaluation and clinical utility of on-site monitoring of coagulation in patients undergoing cardiac operation
J. Thorac. Cardiovasc. Surg., January 1, 1994; 107(1): 271 - 279.
[Abstract] [Full Text]




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 1990 by The Society of Thoracic Surgeons.