ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Astudillo, J.
Right arrow Articles by Conill, C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Astudillo, J.
Right arrow Articles by Conill, C.

Ann Thorac Surg 1990;50:618-623
© 1990 The Society of Thoracic Surgeons

Articles

Role of postoperative radiation therapy in stage IIIa non-small cell lung cancer

Julio Astudillo, MD*, Carlos Conill, MD

Departments of Thoracic Surgery and Radiotherapy, Hospital General Vall d'Hebrón, Barcelona, Spain

Accepted for publication June 1, 1990.

* Address reprint requests to Dr Astudillo, Department of Thoracic Surgery, Hospital General Vall d'Hebrón, 08035 Barcelona, Spain.

One hundred forty-six patients with pathological stage IIIa non-small cell lung cancer were retrospectively analyzed to determine whether postoperative radiation therapy improves survival and reduces locoregional recurrences. The survival rate of the overall group at 1, 3, and 5 years was 56%, 24%, and 17%, respectively. Regarding the type of resection and histology, we did not observe statistically significant differences. Patients with N0 and N1 disease were grouped and compared with the N2 group, and survival at 3 and 5 years was 41% and 27%, respectively, for the T3 N0-1 group and 17% and 15%, respectively, for the T3 N2 group (p < 0.001 and p = 0.05, respectively). Eighty-six patients received postoperative irradiation (45 to 50 Gy) and 60 did not. We have not observed any improvement in survival with postoperative radiation therapy, except in those patients with N2 disease. Median survival time was 6 months for patients without irradiation and 15 months for those with irradiation (p = 0.071). According to locoregional recurrences, a slight benefit with postoperative radiation therapy was observed.




This article has been cited by other articles:


Home page
 The OncologistHome page
C. Le Pechoux
Role of Postoperative Radiotherapy in Resected Non-Small Cell Lung Cancer: A Reassessment Based on New Data
Oncologist, May 1, 2011; 16(5): 672 - 681.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
J. H. Lee, M. Machtay, L. R. Kaiser, J. S. Friedberg, S. M. Hahn, M. G. McKenna, and W. G. McKenna
Non-Small Cell Lung Cancer: Prognostic Factors in Patients Treated with Surgery and Postoperative Radiation Therapy
Radiology, December 1, 1999; 213(3): 845 - 852.
[Abstract] [Full Text]

Home page
 ChestHome page
M. Machtay, L. R. Kaiser, and E. Glatstein
Is Meta-Analysis Really Meta-Physics?
Chest, August 1, 1999; 116(2): 539 - 542.
[Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
D. E. Van Raemdonck, A. Schneider, and R. J. Ginsberg
Surgical treatment for higher stage non-small cell lung cancer
Ann. Thorac. Surg., November 1, 1992; 54(5): 999 - 1013.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 1990 by The Society of Thoracic Surgeons.