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The Annals of Thoracic Surgery, Vol 50, 110-120, Copyright © 1990 by The Society of Thoracic Surgeons
N Shapira, GM Lemole, J Fernandez, PO Daily, WP Dembitsky, V O'Yek, P Haghighi, J Stewart, DG Marsh and CM Bloor
The stenotic aortic valve was surgically repaired in 48 adults, 21 women
and 27 men, aged 38 to 83 years. Five had congenital aortic stenosis (AS),
with a mean aortic valve gradient and area of 58 +/- 23 mm Hg (standard
deviation) and 0.54 +/- 0.13 cm2, respectively; 32 had senile AS with a
mean aortic valve gradient and area of 43 +/- 20 mm Hg and 0.98 +/- 0.41
cm2; and 11 had rheumatic AS with a mean aortic valve gradient and area of
59 +/- 24 mm Hg and 0.47 +/- 0.15 cm2. Only 6 patients underwent isolated
aortic valvoplasty, 11 underwent concomitant mitral valve procedure, and 34
underwent concomitant coronary revascularization. Repair consisted of
decalcification in 33 patients and decalcification as well as
commissurotomy in 15 patients. There were three hospital deaths, none
related to the aortic valve. Only 2 patients (both rheumatic) did not
improve clinically. During follow-up (mean, 64 +/- 41 months) aortic valve
restenosis developed in 24% (10 patients, 3/5 congenital, 4/11 rheumatic,
and 3/32 senile) at a mean of 64 +/- 28 months. Postoperative Doppler
echocardiographic assessment of 21 patients with senile AS at 1.1 +/- 2.7
and 18.1 +/- 1.4 months showed significantly lower aortic valve gradient
and improved area in comparison with preoperative values. At 36 +/- 2.7
months, aortic valve gradient and area were not significantly different
than preoperative values, and at 58.5 +/- 2.6 months aortic valve gradient
was 1.41 (p = 0.07) times the preoperative value. At 7 years, actuarial
freedom from aortic valve-related symptoms of the patients with senile AS
was 87%. We conclude that in select patients aortic valve repair results in
excellent relief of AS. Late restenosis is expected and more likely to
occur in the valves with congenital and rheumatic disease than in those
with senile disease.
ARTICLES
Aortic valve repair for aortic stenosis in adults
Section of Cardiac Surgery, Medical Center, Wilmington, Delaware.
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