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Ann Thorac Surg 1990;49:984-986
© 1990 The Society of Thoracic Surgeons

Articles

Can AIDS be prevented after injury with contaminated instruments?

Francis Robicsek, MD, G.Duke Duncan, PhD, Thomas N. Masters, PhD, Steven A. Robicsek, MS, Harold E. Rice, RT

Carolinas Heart Institute and the Heineman Medical Research Laboratory, Charlotte Memorial Hospital and Medical Center, Charlotte, North Carolina USA

Accepted for publication January 17, 1990.

Particulate matter comparable in size with that of human immunodeficiency virus was subcutaneously injected into experimental animals. Such matter remained at the inoculation site long enough to suggest the possibility that human immunodeficiency virus can be destroyed in loco before it invades the host's circulation. These findings may be useful in developing a method to prevent acquired immunodeficiency syndrome after accidental injury with human immunodeficiency virus-contaminated instruments.




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