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Nasser K. Altorki
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Ann Thorac Surg 1990;49:724-727
© 1990 The Society of Thoracic Surgeons


Articles

Indications for esophagectomy in nonmalignant Barrett's esophagus: A 10-year experience

Nasser K. Altorki, MD*,a,b,c, David B. Skinner, MDa,b,c, Andrea Segalin, MDa,b,c, Janet K. Stephens, MDa,b,c, Mark K. Ferguson, MDa,b,c, Alex G. Little, MDa,b,c

a Department of Surgery, Cornell Medical College, New York, New York, USA
b Department of Surgery, The University of Chicago Medical Center, Chicago, Illinois, USA
c Department of Surgery, University of Nevada School of Medicine, Las Vegas, Nevada, USA

* Address reprint requests to Dr Altorki, 525 East 68th St, New York, NY 10021.

Between 1978 and 1988, 88 patients were referred for the surgical treatment of nonmalignant Barrett's esophagus. Nineteen patients required esophageal resection. Male/female ratio was 13:6; age range was 13 to 84 years (mean age, 49.8 years; median age, 40 years). Preoperative studies demonstrated strictures in 11 patients and ulcers in 7. Penetrating Barrett's ulcer resistant to treatment was the indication for resection in 5 patients. Ulcers penetrated to the pericardium (1 patient), pulmonary vein (1), lung (1), and mediastinum (2). Other indications for resection included undilatable strictures (2), previous operations (4), high-grade dysplasia (3), parietal cells lining the esophagus (1), patient's refusal of long-term surveillance (2), and the inability to exclude adenocarcinoma preoperatively (2). Reconstruction was achieved by colon interposition (15) or esophagogastrostomy (4), with one postoperative death. Mean follow-up was 41 months and was 100% complete. Of the 18 patients, 3 have occasional regurgitation but none have any dysphagia or weight loss. Esophageal resection is indicated in a select group of patients with Barretts esophagus. Absolute indications include a deep penetrating ulcer confirmed intraoperatively, high-grade dysplasia, strong suspicion of cancer, and multiple previous operations. Relative indications include strictures not responding to dilation and young patients refusing long-term surveillance.




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