HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Bonfils-Roberts, E. A. Articles by Nealon, T. F. Search for Related Content PubMed PubMed Citation Articles by Bonfils-Roberts, E. A. Articles by Nealon, T. F., Jr

The Annals of Thoracic Surgery, Vol 49, 115-117, Copyright © 1990 by The Society of Thoracic Surgeons

ARTICLES

Retrospective analysis of the efficacy of open lung biopsy in acquired immunodeficiency syndrome

EA Bonfils-Roberts, A Nickodem and TF Nealon Jr
Department of Surgery, St. Vincent's Hospital, New York, NY.

Open lung biopsy (OLB) was performed on 66 patients with acquired immunodeficiency syndrome from November 1981 through December 1987. Twenty-two patients with severe respiratory failure died within a month, 3 during operation. Fourteen patients with negative transbronchial biopsy and 19 with failure of treatment based on transbronchial biopsy died within a year. Six were alive and 5 were lost to follow-up. The most common organism found in patients with severe respiratory failure was Pneumocystis carinii alone or with other pathogens. Successful therapeutic change based on OLB findings was possible in only 1 (1.5%) of the 66 patients. Open lung biopsy has limited application in the management of acquired immunodeficiency syndrome. In patients with overt pulmonary failure, OLB is invariably fatal. Those seen with suspicious lung infiltrates without risk factors or with known risk factors and negative transbronchial biopsy results might benefit from OLB. In our institution, 18 of 64 acquired immunodeficiency syndrome admissions underwent OLB in 1983, whereas in 1987, only 2 of 302 patients admitted with acquired immunodeficiency syndrome had OLB.

This article has been cited by other articles:

				A. Ahmad, S. Khan, and A. O. Soubani The Findings of Surgical Lung Biopsy in HIV Patients in the Era of Highly Active Antiretroviral Therapy Ann. Thorac. Surg., June 1, 2005; 79(6): 1862 - 1865. [Abstract] [Full Text] [PDF]

				M.-L. Chuang, I-F. Lin, Y.-H. Tsai, J. R. E. Vintch, and L.-C. Pang The Utility of Open Lung Biopsy in Patients With Diffuse Pulmonary Infiltrates as Related to Respiratory Distress, Its Impact on Decision Making by Urgent Intervention, and the Diagnostic Accuracy Based on the Biopsy Location J Intensive Care Med, January 1, 2003; 18(1): 21 - 28. [Abstract] [PDF]