|
|
||||||||
The Annals of Thoracic Surgery, Vol 48, 803-812, Copyright © 1989 by The Society of Thoracic Surgeons
S Gabbay, AM Guindy, JF Andrews, JJ Amato, P Seaver and MY Khan
The difficulties of reoperation owing to adhesions are well known. Clinical
attempts to solve this problem using synthetic materials or
glutaraldehyde-fixed pericardial xenograft have been less than
satisfactory. Although experimental animal results have been good, they
have not considered the influence of cardiopulmonary bypass (CPB) on
adhesion formation. This study addressed the influence of CPB on the
formation of adhesions and evaluated biodegradable polyglycolic acid as a
material to reduce adhesions and as a pericardial substitute. Forty- five
weanling sheep received implants of pericardial xenograft and polyglycolic
acid with and without CPB. The pericardial xenograft showed no adhesions
when implanted without CPB, but severe adhesions formed and a thick
fibrinous layer covered the heart when CPB was used, making identification
of coronary arteries at reoperation very difficult. The polyglycolic acid
mesh implanted without CPB was absorbed and replaced with newly formed host
collagen. With CPB, the polyglycolic acid was more rapidly absorbed, and a
thinner layer of host collagen formed. Therefore, future animal studies
must include CPB. In agreement with reported clinical results,
glutaraldehyde-fixed pericardial tissue implanted with CPB resulted in
severe epicardial reaction and therefore is not an ideal pericardial
substitute.
ARTICLES
New outlook on pericardial substitution after open heart operations
Department of Surgery, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark 07103.
This article has been cited by other articles:
![]() |
G. Matsumura, T. Shin'oka, Y. Ikada, T. Sakamoto, and H. Kurosawa Novel Anti-Adhesive Pericardial Substitute for Multistage Cardiac Surgery Asian Cardiovasc Thorac Ann, August 1, 2008; 16(4): 309 - 312. [Abstract] [Full Text] [PDF] |
||||
![]() |
Y. Naito, T. Shin'oka, N. Hibino, G. Matsumura, and H. Kurosawa A novel method to reduce pericardial adhesion: A combination technique with hyaluronic acid biocompatible membrane. J. Thorac. Cardiovasc. Surg., April 1, 2008; 135(4): 850 - 856. [Abstract] [Full Text] [PDF] |
||||
![]() |
Y. Chang, P.-H. Lai, C.-C. Wang, S.-C. Chen, W.-C. Chang, and H.-W. Sung Mesothelium regeneration on acellular bovine pericardia loaded with an angiogenic agent (ginsenoside Rg1) successfully reduces postsurgical pericardial adhesions J. Thorac. Cardiovasc. Surg., October 1, 2006; 132(4): 867 - 874. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. Tsukihara, S. Takamoto, K. Kitahori, K. Matsuda, A. Murakami, R. J. Novick, and Y. Suematsu Prevention of Postoperative Pericardial Adhesions With a Novel Regenerative Collagen Sheet Ann. Thorac. Surg., February 1, 2006; 81(2): 650 - 657. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. Sakuma, A. Iguchi, Y. Ikada, and K. Tabayashi Closure of the Pericardium Using Synthetic Bioabsorbable Polymers Ann. Thorac. Surg., November 1, 2005; 80(5): 1835 - 1840. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. Saha, W. McEwan, F. A Frizelle, and H. Singh Limiting Pericardial Adhesions after Coronary Artery Bypass: Experimental Study Asian Cardiovasc Thorac Ann, March 1, 2004; 12(1): 61 - 64. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Endo, N. Saito, Y. Misawa, and Y. Sohara Late pericarditis secondary to pericardial patch implantation 25 years prior Eur. J. Cardiothorac. Surg., November 1, 2001; 20(5): 1059 - 1060. [Abstract] [Full Text] [PDF] |
||||
![]() |
N. Okuyama, C. Y. Wang, E. A. Rose, K. E. Rodgers, E. Pines, G. S. diZerega, and M. C. Oz Reduction of retrosternal and pericardial adhesions with rapidly resorbable polymer films Ann. Thorac. Surg., September 1, 1999; 68(3): 913 - 918. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. Lahtinen, J. Satta, S. Lahde, I. Suramo, J. Nissinen, R. Pokela, and T. Juvonen Computed tomographic evaluation of retrosternal adhesions after pericardial substitution Ann. Thorac. Surg., October 1, 1998; 66(4): 1264 - 1268. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. Hurle, M. de la Vega, J. J. Feijoo, V. G. Ray, C. Abad, G. Ponce, and J. L. Perez-Arellano Effect of Physical Protection on the Mesothelial Integrity of the Pericardium Ann. Thorac. Surg., April 1, 1997; 63(4): 1091 - 1094. [Abstract] [Full Text] |
||||
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| ANN THORAC SURG | ASIAN CARDIOVASC THORAC ANN | EUR J CARDIOTHORAC SURG |
| J THORAC CARDIOVASC SURG | ICVTS | ALL CTSNet JOURNALS |