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The Annals of Thoracic Surgery, Vol 48, 518-522, Copyright © 1989 by The Society of Thoracic Surgeons
T Fujiwara, A Nogami, H Masaki, H Yamane, S Matsuoka, H Yoshida, H Fukuda, T Katsumura and F Kajiya
In 6 patients with pure aortic stenosis, the flow velocity waveforms in the
left anterior descending coronary artery were studied using an 80- channel
20-MHz pulsed Doppler velocimeter before and immediately after aortic valve
replacement. All patients showed normal coronary arteriograms. The left
anterior descending coronary artery flow velocity waveform in aortic
stenosis was characterized by a reverse flow in the first half of systole
and a slowly increasing diastolic inflow. After aortic valve replacement,
the reverse flow in the first half of systole disappeared in all patients,
but an end-systolic reverse flow was discerned in 5 of 6 patients. The
increasing rate of the diastolic inflow was augmented in all patients.
After aortic valve replacement, the time from onset of diastole to the
diastolic peak velocity was shortened from 176.8 +/- 28.8 to 90.5 +/- 18.8
ms (p less than 0.01), and the diastolic peak velocity increased from 90.5
+/- 28.0 to 122.5 +/- 17.2 cm/s (p less than 0.05). Blood pressure and
heart rate, however, did not change significantly before and after valve
replacement. These changes in the left coronary artery velocity waveforms
after valve replacement suggest the beneficial effects of removal of aortic
stenosis on human coronary artery inflow.
ARTICLES
Coronary flow velocity waveforms in aortic stenosis and the effects of valve replacement
Department of Thoracic Surgery, Kawasaki Medical School, Kurashiki, Japan.
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