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Ann Thorac Surg 1989;48:345-349
© 1989 The Society of Thoracic Surgeons

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Articles

Aortic Valve and Left Ventricular Outflow Tract Replacement Using Allograft and Autograft Valves: A Preliminary Report

Division of Thoracic Surgery, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

^* Address reprint requests to Dr Randolph, Division of Thoracic Surgery, Oklahoma Health Science Center, PO Box 26901, Oklahoma City, OK 73190

A comparison of allograft and autograft (pulmonary) replacement of the aortic valve has, to our knowledge, not been done in America. Fifty-seven patients (age range, 2 to 70 years; mean age, 30 years) underwent 59 operations for replacement of the aortic valve (20) or entire left ventricular outflow tract (39) using autograft (35) or allograft (24) valves. Many had undergone a previous operation (25) or had concomitant procedures (13). Postoperative mortality was 8.5% (5/59). Two deaths occurred in the allograft group and three in the more complex pulmonary autograft group. One late death occurred. One autograft was replaced with an allograft 7 months postoperatively for severe aortic regurgitation. There have been no episodes of either endocarditis or thromboembolism. Forty-nine of 51 survivors are in New York Heart Association class I. Preliminary results suggest that congenital or acquired disease of the left ventricular outflow tract and aortic valve can be safely and effectively treated with either allograft or autograft valve transplantation.

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