HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Gray, L. A. Articles by Slater, A. D. Search for Related Content PubMed PubMed Citation Articles by Gray, L. A., Jr Articles by Slater, A. D.

The Annals of Thoracic Surgery, Vol 48, 222-227, Copyright © 1989 by The Society of Thoracic Surgeons

ARTICLES

The Pierce-Donachy ventricular assist device as a bridge to cardiac transplantation

LA Gray Jr, BL Ganzel, C Mavroudis and AD Slater
Department of Surgery, University of Louisville School of Medicine, Kentucky.

The Pierce-Donachy ventricular assist device (VAD) was used as an attempted bridge to orthotopic cardiac transplantation in 12 patients aged 13 to 55 years. Ischemic (4 patients), dilated (4 patients), acute viral (1 patient), postpartum (1 patient), and hypertrophic cardiomyopathy (1 patient), along with a failed transplant (1 patient), were the causative factors of end-stage cardiomyopathy in these patients. All patients were candidates for orthotopic cardiac transplantation but sustained refractory cardiogenic shock (cardiac index less than 2 L/min/m2). Left VADs were placed in all patients; 7 also required right VADs. Four patients died of hemorrhagic complications less than 24 hours after VAD insertion. Ventricular assist device stabilization was successful in 8 patients and support ranged from eight hours to 64 days. Seven patients successfully underwent orthotopic cardiac transplantation. One died postoperatively of hemorrhagic complications, 6 were discharged from the hospital, and 1 patient died at 3 months of cytomegalovirus infection. Five patients are long-term survivors. The Pierce-Donachy VAD is an effective means for supporting critically ill patients with end-stage cardiomyopathy and cardiogenic shock before orthotopic cardiac transplantation. Death is related to hemorrhagic, rather than infectious or thromboembolic, complications. Patients successfully stabilized with the VAD can undergo orthotopic cardiac transplantation with acceptable mortality and morbidity rates.

This article has been cited by other articles:

				A. El-Banayosy, H. Posival, K. Minami, L. Arusoglu, L. Kizner, T. Breymann, D. Seifert, M. Korner, H. Kortke, O. Fey, et al. Mechanical circulatory support: lessons from a single centre Perfusion, March 1, 1996; 11(2): 93 - 102. [Abstract] [PDF]

				W. L. Holman, C. P. Murrah, E. R. Ferguson, R. C. Bourge, D. C. McGiffin, and J. K. Kirklin Infections During Extended Circulatory Support: University of Alabama at Birmingham Experience 1989 to 1994 Ann. Thorac. Surg., January 1, 1996; 61(1): 366 - 371. [Abstract] [Full Text]