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The Annals of Thoracic Surgery, Vol 48, 186-191, Copyright © 1989 by The Society of Thoracic Surgeons
AJ Acinapura, DM Rose, IJ Jacobowitz, MD Kramer, RR Robertazzi, J Feldman, Z Zisbrod and JN Cunningham
Internal mammary artery (IMA) bypass grafting to the anterior descending
coronary artery was performed in 2,100 patients between January 1978 and
July 1986. The average number of additional saphenous vein grafts (SVGs)
per patient was 1.8. During the same period, 1,753 patients underwent
coronary artery bypass grafting using an SVG (average number of grafts per
patient, 3.2). The average patient age was similar: 62.3 years for IMA
grafts and 64.7 years for SVGs. Men constituted two thirds of each group.
Left ventricular function was impaired (ejection fraction less than 45%) in
1,071 (51%) of IMA grafts and 847 (48.3%) of SVGs. Other aggregate risk
factors, ie, elevated blood pressure, diabetes mellitus, previous
myocardial infarction, and congestive heart failure, were similar in each
group. Operative results and postoperative mortality of the IMA and SVG
patients were comparable. However, the long-term probability of cumulative
survival and occlusion-free survival were significantly greater and the
probability of recurrent angina and reoperative coronary artery bypass
grafting were significantly less in IMA graft patients (p less than 0.015).
The relative risk of occlusion in an SVG was 4 to 5 times greater than that
of the IMA graft. These data indicate that a patent IMA graft to the
anterior descending coronary artery protects against recurrent angina and
death from cardiac-related causes, and that the IMA should be the conduit
of choice.
ARTICLES
Internal mammary artery bypass grafting: influence on recurrent angina and survival in 2,100 patients
Department of Cardiac Surgery, St. Vincent's Hospital and Medical Center, New York, New York 10011.
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