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Ann Thorac Surg 1989;48:54-59
© 1989 The Society of Thoracic Surgeons


Articles

A 10-year comparison of mitral valve replacement with Carpentier-Edwards and Hancock porcine bioprostheses

P. Perier, MD*, A. Deloche, MD, S. Chauvaud, MD, J.C. Chachques, MD, J. Relland, MD, J.N. Fabiani, MD, Y. Stephan, MD, P. Blondeau, MD, A. Carpentier, MD, PhD

Department of Cardiovascular Surgery, Hôpital Eroussais, Paris, France

Accepted for publication January 20, 1989.

* Address reprint requests te Dr Perier, Clinique de Chirurgie Cardio-Vasculaire Hôpital Broussais, 96, rue Didot, 75014 Paris, France.

Two hundred fifty-three patients who underwent isolated mitral valve replacement with a porcine bioprosthesis had long-term evaluation. One hundred forty-seven patients received a Carpentier-Edwards porcine bioprosthesis and 106, a Hancock valve. There were no significant differences in preoperative clinical characteristics between the two groups. Cumulative follow-up was 1,375 patient-years. At 10 years, 93% ± 2.5% of the patients in the Carpentier-Edwards group and 85% ± 7.8% of those in the Hancock group were free from valve-related death (not significant), and 95% ± 2% and 91% ± 3.8%, respectively, were free ton thromboembolism (not significant). At 10 years, 65% ± 7.2% of the patients in the Carpentier-Edwards group and 66% ± 7.2% of those in the Hancock group were free from structural valve deterioration (not significant), and 64% ± 6% and 59% ± 7.3%, respectively, were free from reoperation (not significant). We conclude that the first generation of Carpentier-Edwards and Hancock prostheses produce comparable long-term results in the mitral position.




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