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The Annals of Thoracic Surgery, Vol 48, 54-59, Copyright © 1989 by The Society of Thoracic Surgeons

ARTICLES

A 10-year comparison of mitral valve replacement with Carpentier- Edwards and Hancock porcine bioprostheses

P Perier, A Deloche, S Chauvaud, JC Chachques, J Relland, JN Fabiani, Y Stephan, P Blondeau and A Carpentier
Department of Cardiovascular Surgery, Hopital Broussais, Paris, France.

Two hundred fifty-three patients who underwent isolated mitral valve replacement with a porcine bioprosthesis had long-term evaluation. One hundred forty-seven patients received a Carpentier-Edwards porcine bioprosthesis and 106, a Hancock valve. There were no significant differences in preoperative clinical characteristics between the two groups. Cumulative follow-up was 1,375 patient-years. At 10 years, 93% +/- 2.5% of the patients in the Carpentier-Edwards group and 85% +/- 7.8% of those in the Hancock group were free from valve-related death (not significant), and 95% +/- 2% and 91% +/- 3.8%, respectively, were free from thromboembolism (not significant). At 10 years, 65% +/- 7.2% of the patients in the Carpentier-Edwards group and 66% +/- 7.2% of those in the Hancock group were free from structural valve deterioration (not significant), and 64% +/- 6% and 59% +/- 7.3%, respectively, were free from reoperation (not significant). We conclude that the first generation of Carpentier-Edwards and Hancock prostheses produce comparable long-term results in the mitral position.


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