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The Annals of Thoracic Surgery, Vol 48, 33-37, Copyright © 1989 by The Society of Thoracic Surgeons
R Wahi, MJ McMurtrey, LF DeCaro, CF Mountain, MK Ali, TL Smith and JA Roth
A total of 197 consecutive patients undergoing pneumonectomy at the M.D.
Anderson Cancer Center from 1982 to 1987 were reviewed. Sixty-five
variables were analyzed for the predictive value for perioperative risk.
The operative mortality rate was 7% (14/197). Patients having a right
pneumonectomy (n = 95) had a higher operative mortality rate (12%) than
patients having a left pneumonectomy (1%, p less than 0.05). The extent of
resection correlated with the operative mortality rate (chest wall
resection or extrapleural pneumonectomy, n = 39, 15%; versus simple or
intrapericardial pneumonectomy, n = 158, 5%; p less than 0.05). Patients
whose predicted postoperative pulmonary function, by spirometry and xenon
133 regional pulmonary function studies, was a forced expiratory volume in
1 second greater than 1.65 L, forced expiratory volume in 1 second greater
than 58% of the preoperative value, forced vital capacity greater than 2.5
L, or forced vital capacity greater than 60% of the preoperative value had
a lower operative mortality rate (p less than 0.05). Atrial arrhythmia was
the most common postoperative complication (23%). Xenon 133 regional
pulmonary function studies are useful in predicting the risks of
pneumonectomy.
ARTICLES
Determinants of perioperative morbidity and mortality after pneumonectomy
Department of Thoracic Surgery, University of Texas, M.D. Anderson Cancer Center, Houston 77030.
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