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The Annals of Thoracic Surgery, Vol 47, 477-480, Copyright © 1989 by The Society of Thoracic Surgeons
DW McFadden, M Rudnicki and MA Talamini
A primary small cell carcinoma of the esophagus in a 61-year-old woman was
treated by transhiatal esophagectomy. The clinical data were correlated
with data obtained from a review of the 129 cases reported in the world
literature, thereby providing a clinical profile and suggested management
strategy for this rare type of esophageal malignancy. Presenting symptoms
of esophageal small cell carcinoma include dysphagia (75.3%), weight loss
(38.4%), and chest pain (23.3%). Treatment regimens have included surgical
intervention in 58%, radiotherapy in 10%, chemotherapy in 6%, or some
combination of these in 26%. Overall survival is only 20.7 weeks after
diagnosis. The fact that three fourths of affected patients had metastatic
disease at the time of diagnosis leads us to recommend surgical
intervention plus systemic chemotherapy in these patients.
ARTICLES
Primary small cell carcinoma of the esophagus
Department of Surgery, University of Cincinnati Medical Center, Ohio 45267.
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