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Ann Thorac Surg 1988;46:416-419
© 1988 The Society of Thoracic Surgeons

Articles

Autologous Platelet-Rich Plasma in Cardiac Surgery: Effect on Intraoperative and Postoperative Transfusion Requirements

Gerald F. Giordano, M.D.*, Shirley L. Rivers, M.D., George K.T. Chung, M.D., Robert B. Mammana, M.D., Joseph D. Marco, M.D., Allen R. Raczkowski, M.D., Adib Sabbagh, M.D., Richard G. Sanderson, M.D., Burt S. Strug, M.D.

Southern Arizona Regional Red Cross Blood Program; The Carondelet Health Care System; El Dorado Hospital and Medical Center; and Tucson Medical Center, Tucson, AZ

Accepted for publication April 18, 1988.

* Address reprint requests to Dr. Giordano, Southern Arizona Regional Red Cross Blood Program, 220 S. Cherry Ave, Tucson, AZ 85719

The Southern Arizona Red Cross Blood program, in conjunction with participating hospitals and cardiac surgeons, evaluated the effect of a program to harvest autologous platelet-rich plasma (PRF) from patients immediately prior to undergoing cardiopulmonary bypass surgery. The PRP was transfused back to the patient after heparin neutralization was achieved at the completion of cardiopulmonary bypass. The effect of this autologous PRP product on homologous plasma and platelet usage was examined. The study demonstrates a significant decrease in homologous plasma and platelet usage when autologous PRP is used in cardiac surgery.




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