HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Author home page(s): Aldo D. Milano Uberto Bortolotti Alessandro Mazzucco Francisco Guerra Giovanni Stellin Gaetano Thiene Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Milano, A. D. Articles by Gallucci, V. Search for Related Content PubMed PubMed Citation Articles by Milano, A. D. Articles by Gallucci, V.

Ann Thorac Surg 1988;46:216-222
© 1988 The Society of Thoracic Surgeons

---

Articles

Performance of the Hancock Porcine Bioprosthesis Following Aortic Valve Replacement: Considerations Based on a 15-Year Experience

From the Departments of Cardiovascular Surgery, Radiology, and Pathology, University of Padova Medical School, Padova, Italy

Accepted for publication February 9, 1988.

^* Address reprint requests to Dr. Bortolotti, Istituto di Chirurgia Cardiovascolare, Università di Padova, Via Giustiniani, 2, 35128 Padova, Italy.

All patients undergoing isolated aortic valve replacement with a standard Hancock porcine bioprosthesis (PB), from 1970 to 1983, were reviewed. There were 196 patients, 162 male and 34 female patients, with a mean age of 48 ± 12 years. Operative survivors were followed up from 3 to 15.6 years (mean follow-up, 6.6 ± 1.5 years), with a cumulative follow-up of 1,140 patient-years, being 100% complete.

Actuarial survival was 51 ± 15% at 14 years. Eight patients sustained systemic embolic episodes (0.7 ± 0.2%/patient-year); actuarial freedom from emboli is 89.4 ± 4.3% at 14 years. Reoperation was performed in 53 patients: in 6 because of endocarditis (0.5 ± 0.2%/patient-year), in 7 because of perivalvular leak (0.6 ± 0.2%/patient-year), and in 40 because of PB primary tissue failure (3.5 ± 0.5%/patient-year). Actuarial freedom from PB-related deaths, PB failure, and overall PB-related complications at 14 years was 66.3 ± 19, 34.3 ± 11, and 30 ± 10%, respectively.

This long-term experience shows that the performance of the Hancock PB appears satisfactory up to 8 years, while it progressively deteriorates beyond 10 years because of the impact of primary tissue failure on valve durability, justifying the restriction of its use in the aortic position in selected patients.

This article has been cited by other articles:

				N. D. Desai and G. T. Christakis Stented Mechanical/Bioprosthetic Aortic Valve Replacement Card. Surg. Adult, January 1, 2003; 2(2003): 825 - 856. [Full Text]

				B. Yamak, B. Mavitas, A. Saritas, S F. Katircioglu, A T. Ulus, L. Birincioglu, Y H. Karagoz, E. Sener, O. Tasdemir, and K. Bayazit Ten-Year Results With Liotta Porcine Bioprostheses in the Mitral Position Asian Cardiovasc Thorac Ann, December 1, 1998; 6(4): 260 - 264. [Abstract] [Full Text] [PDF]

				G. B. Luciani, P. Bertolini, and A. Mazzucco EARLY FAILURE OF FREEHAND AORTIC STENTLESS XENOGRAFT VALVES J. Thorac. Cardiovasc. Surg., June 1, 1997; 113(6): 1109 - 1110. [Full Text]

				J. I. Fann, D. C. Miller, KathleenA. Moore, R. S. Mitchell, P. E. Oyer, E. B. Stinson, R. C. Robbins, B. A. Reitz, and N. E. Shumway Twenty-Year Clinical Experience With Porcine Bioprostheses Ann. Thorac. Surg., November 1, 1996; 62(5): 1301 - 1311. [Abstract] [Full Text]

				K. L. Yun, D. Craig Miller, K. A. Moore, R. Scott Mitchell, P. E. Oyer, E. B. Stinson, R. C. Robbins, B. A. Reitz, and N. E. Shumway Durability of the hancock MO bioprosthesis compared with standard aortic valve bioprostheses Ann. Thorac. Surg., August 1, 1995; 60(suppl_2): S221 - S228. [Abstract] [PDF]

				U. Bortolotti, A. Milano, G. Thiene, and A. Mazzucco Original expectations of the Hancock valve and 20 years of clinical reality Eur J Cardiothorac Surg, January 1, 1992; 6(Supplement_1): S75 - S78. [Abstract] [PDF]

				U. Bortolotti, A. Milano, L. Testolin, V. Tursi, A. Mazzucco, and V. Gallucci Influence of type of prosthesis on late results after combined mitral-aortic valve replacement Ann. Thorac. Surg., July 1, 1991; 52(1): 84 - 91. [Abstract] [PDF]

				E. L. Jones, W. S. Weintraub, J. M. Craver, R. A. Guyton, C. L. Cohen, V. E. Corrigan, and C. R. Hatcher Jr Ten-year experience with the porcine bioprosthetic valve: Interrelationship of valve survival and patient survival in 1,050 valve replacements Ann. Thorac. Surg., March 1, 1990; 49(3): 370 - 384. [Abstract] [PDF]

				D. J. Magilligan Jr, J. W. Lewis Jr, P. Stein, and M. Alam The Porcine Bioprosthetic Heart Valve: Experience at 15 Years Ann. Thorac. Surg., September 1, 1989; 48(3): 324 - 330. [Abstract] [PDF]

				K. V. Arom, D. M. Nicoloff, T. E. Kersten, W. F. Northrup III, W. G. Lindsay, and R. W. Emery Ten years' experience with the St. Jude Medical valve prosthesis Ann. Thorac. Surg., June 1, 1989; 47(6): 831 - 837. [Abstract] [PDF]

				L. C. Pelletier, M. Carrier, Y. Leclerc, G. Lepage, P. deGuise, and I. Dyrda Porcine versus pericardial bioprostheses: A comparison of late results in 1,593 patients Ann. Thorac. Surg., March 1, 1989; 47(3): 352 - 361. [Abstract] [PDF]