ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
Jakob Vinten-Johansen
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Johnston, W. E.
Right arrow Articles by Moulton, K. P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Johnston, W. E.
Right arrow Articles by Moulton, K. P.

Ann Thorac Surg 1988;45:667-673
© 1988 The Society of Thoracic Surgeons

Articles

Efficacy of Intravascular Volume Resuscitation in Dogs with Acute Cardiac Tamponade

William E. Johnston, M.D.*, Jakob Vinten-Johansen, Ph.D., Andrew C. McGivor, B.S., William P. Santamore, Ph.D., Steven M. Block, M.D., Kreigh P. Moulton, M.D.

Departments of Anesthesia, Surgery, Pediatrics, and Medicine, Wake Forest University Medical Center, Winston-Salem, NC

Accepted for publication December 30, 1987.

* Address reprint requests to Dr. Johnston, Department of Anesthesia, Wake Forest University Medical Center, 300 South Hawthorne Rd, Winston-Salem, NC 27103

Whether cardiac tamponade causes myocardial ischemia and whether volume resuscitation can improve coronary perfusion pressure and myocardial blood flow were studied by hemodynamic responses to three blood infusions of 15 ml/kg in dogs with left ventricular hypovolemia produced by cardiac tamponade (N = 10) or hemorrhage (N = 10). Coronary perfusion pressure decreased to 37 ± 2 mm Hg with tamponade and 39 ± 1 mm Hg with hemorrhage, causing significant blood flow decreases in both ventricles. Myocardial oxygen extraction increased significantly in both groups without affecting lactate extraction. Volume resuscitation after hemorrhage progressively restored hemodynamic variables to baseline values. Volume resuscitation after tamponade did not increase stroke volume, whereas it increased coronary sinus pressure to 19.2 ± 1.0 mm Hg (p < 0.05). Coronary perfusion pressure increased to 53 ± 5 mm Hg following the first infusion (p < 0.05), but exhibited no further improvement. Tamponade did not produce myocardial ischemia. Coronary perfusion pressure and blood flow were not restored to baseline values with volume resuscitation since coronary sinus pressure rose incrementally with each volume infusion.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 1988 by The Society of Thoracic Surgeons.