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Ann Thorac Surg 1988;45:554-558
© 1988 The Society of Thoracic Surgeons

Articles

Initial Experimental Experience with a "Replaceable" Cardiac Valve Prosthesis

D.K.C. Cooper, M.D., Ph.D., F.R.C.S.*, W.N. Wicomb, Ph.D., Gwyneth M. Gould, D. Boonzaier, M.B.

From the Departments of Cardiothoracic Surgery and Biomedical Engineering, Groote Schuur Hospital and the University of Cape Town Medical School, Cape Town, South Africa

Accepted for publication December 9, 1987.

* Address reprint requests to Dr. Cooper, Oklahoma Transplantation Institute, Baptist Medical Center, 3300 Northwest Expressway, Oklahoma City, OK 73112

An easily "replaceable" cardiac valve prosthesis has been designed. It consists of two parts: (1) a sewing ring incorporating a circlip and (2) a functioning valve (either mechanical or tissue). The circlip is encased in a sewing ring, which is sutured into the natural valve annulus, and grips the functional part of the prosthesis, thereby preventing dislodgment. A simple instrument has been designed to open the circlip a few millimeters to allow easy removal or insertion of the functional element. This sewing ring/circlip with the functional element of a Björk-Shiley prosthesis was used in 10 baboons undergoing mitral valve replacement. Removal and replacement of the functional element was carried out at a second operation between 1 and 12 weeks later. There were no operative deaths. Baboons were electively killed one day to twelve months after the second operation. There were no complications related to the prosthesis; cardiac catheterization showed normal hemodynamics before and after the second operative procedure.






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