ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
John W. Hammon, Jr.
Flavian M. Lupinetti
Michael D. Maples
Walter H. Merrill
William H. Frist
Harvey W. Bender, Jr.
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Hammon, J. W.
Right arrow Articles by Bender, H. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hammon, J. W., Jr.
Right arrow Articles by Bender, H. W., Jr.

Ann Thorac Surg 1988;45:537-540
© 1988 The Society of Thoracic Surgeons

Articles

Predictors of Operative Mortality in Critical Valvular Aortic Stenosis Presenting in Infancy

John W. Hammon, Jr., M.D.*, Flavian M. Lupinetti, M.D., Michael D. Maples, M.D., Walter H. Merrill, M.D., William H. Frist, M.D., Thomas P. Graham, Jr., M.D., Harvey W. Bender, Jr., M.D.

From the Department of Cardiac and Thoracic Surgery and the Division of Pediatric Cardiology, Vanderbilt University Medical Center, Nashville, TN

* Address reprint requests to Dr. Hammon, The Vanderbilt Clinic, Nashville, TN 37232

Congenital aortic stenosis presenting within the first 6 months of life is a highly lethal anomaly. Although aortic valvotomy has offered excellent palliation in many instances, the operative risk remains substantial. To better understand the factors associated with a poor operative result, the records of all patients less than 6 months of age undergoing aortic valvotomy at our institution from 1972 through 1986 were analyzed. Nineteen patients (58%) (Group I) survived operation; 14 (42%) (Group II) died. The following variables were analyzed in an attempt to define those with prognostic significance: mean pulmonary artery pressure (PAP), left ventricular (LV) peak systolic pressure, LV end-diastolic pressure, peak systolic aortic valve gradient, LV end-diastolic volume (LVEDV), LV ejection fraction, and age at operation. The only variables that were significantly different in the two groups were mean PA (Group I, 29 ± 3 mm Hg, and Group II, 54 ± 3 mm Hg; p < 0.001) and LVEDV (Group I, 50 ± 8 ml/m2, and Group II, 20 ± 4 ml/m2; p < 0.05). No patient with an LVEDV of 20 ml/m2 or less survived operation. We conclude that small LV dimension and elevation of PAP may be predictive of a poor surgical result in patients with severe aortic stenosis presenting in infancy.




This article has been cited by other articles:


Home page
 Circ Cardiovasc ImagingHome page
M. K. Friedberg, X. Su, W. Tworetzky, B. D. Soriano, A. J. Powell, and G. R. Marx
Validation of 3D Echocardiographic Assessment of Left Ventricular Volumes, Mass, and Ejection Fraction in Neonates and Infants With Congenital Heart Disease: A Comparison Study With Cardiac MRI
Circ Cardiovasc Imaging, November 1, 2010; 3(6): 735 - 742.
[Abstract] [Full Text] [PDF]

Home page
 World Journal for Pediatric and Congenital Heart SurgeryHome page
D. M. Overman, J. M. Baffa, M. S. Cohen, L. Mertens, D. B. Gremmels, A. Jegatheeswaram, B. W. McCrindle, E. H. Blackstone, V. O. Morell, C. Caldarone, et al.
Unbalanced Atrioventricular Septal Defect: Definition and Decision Making
World Journal for Pediatric and Congenital Heart Surgery, April 1, 2010; 1(1): 91 - 96.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
L. Grosse-Wortmann, T.-J. Yun, O. Al-Radi, S. Kim, M. Nii, K.-J. Lee, A. Redington, S.-J. Yoo, and G. van Arsdell
Borderline hypoplasia of the left ventricle in neonates: insights for decision-making from functional assessment with magnetic resonance imaging.
J. Thorac. Cardiovasc. Surg., December 1, 2008; 136(6): 1429 - 1436.
[Abstract] [Full Text] [PDF]

Home page
 Eur J Cardiothorac SurgHome page
B. Alsoufi, T. Karamlou, B. W. McCrindle, and C. A. Caldarone
Management options in neonates and infants with critical left ventricular outflow tract obstruction
Eur J Cardiothorac Surg, June 1, 2007; 31(6): 1013 - 1021.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
S. D. Colan, D. B. McElhinney, E. C. Crawford, J. F. Keane, and J. E. Lock
Validation and Re-Evaluation of a Discriminant Model Predicting Anatomic Suitability for Biventricular Repair in Neonates With Aortic Stenosis
J. Am. Coll. Cardiol., May 2, 2006; 47(9): 1858 - 1865.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
J. W. Brown, M. Ruzmetov, P. Vijay, M. D. Rodefeld, and M. W. Turrentine
Closed Transventricular Aortic Valvotomy for Critical Aortic Stenosis in Neonates: Outcomes, Risk Factors, and Reoperations
Ann. Thorac. Surg., January 1, 2006; 81(1): 236 - 242.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
V. L. Vida, T. Bottio, O. Milanesi, E. Reffo, R. Biffanti, R. Bonato, and G. Stellin
Critical Aortic Stenosis in Early Infancy: Surgical Treatment for Residual Lesions After Balloon Dilation
Ann. Thorac. Surg., January 1, 2005; 79(1): 47 - 51.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
M. D. Puchalski, R. V. Williams, J. A. Hawkins, L. L. Minich, and L. Y. Tani
Follow-up of aortic coarctation repair in neonates
J. Am. Coll. Cardiol., July 7, 2004; 44(1): 188 - 191.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
C. Mavroudis and R. M. Sade
The Southern Thoracic Surgical Association 50th anniversary celebration: the impact of STSA pediatric cardiothoracic surgery manuscripts on surgical practice
Ann. Thorac. Surg., November 1, 2003; 76(90050): S47 - 67.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
B. W. McCrindle, E. H. Blackstone, W. G. Williams, R. Sittiwangkul, T. L. Spray, A. Azakie, and R. A. Jonas
Are Outcomes of Surgical Versus Transcatheter Balloon Valvotomy Equivalent in Neonatal Critical Aortic Stenosis?
Circulation, September 18, 2001; 104(2009): I-152 - I-158.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
M. L. Schwartz, K. Gauvreau, and T. Geva
Predictors of Outcome of Biventricular Repair in Infants With Multiple Left Heart Obstructive Lesions
Circulation, August 7, 2001; 104(6): 682 - 687.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
G. K. Lofland, B. W. McCrindle, W. G. Williams, E. H. Blackstone, C. I. Tchervenkov, R. Sittiwangkul, and R. A. Jonas
Critical aortic stenosis in the neonate: A multi-institutional study of management, outcomes, and risk factors
J. Thorac. Cardiovasc. Surg., January 1, 2001; 121(1): 0010 - 27.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
J.R. Bockoven, G. Wernovsky, V. L. Vetter, T. S. Wieand, T. L. Spray, and L. A. Rhodes
Perioperative conduction and rhythm disturbances after the Ross procedure in young patients
Ann. Thorac. Surg., October 1, 1998; 66(4): 1383 - 1388.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
J. P. Kovalchin, M. M. Brook, G. L. Rosenthal, K. Suda, J. I. E. Hoffman, and N. H. Silverman
Echocardiographic hemodynamic and morphometric predictors of survival after two-ventricle repair in infants with critical aortic stenosis
J. Am. Coll. Cardiol., July 1, 1998; 32(1): 237 - 244.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
J. A. Hawkins, L. L. Minich, L. Y. Tani, R. W. Day, V. E. Judd, R. E. Shaddy, and E. C. McGough
Late Results and Reintervention After Aortic Valvotomy for Critical Aortic Stenosis in Neonates and Infants
Ann. Thorac. Surg., June 1, 1998; 65(6): 1758 - 1762.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
G. Sudow, L. Solymar, H. Berggren, B. Eriksson, D. Holmgren, and T. Gilljam
AORTIC VALVE REPLACEMENT WITH A PULMONARY AUTOGRAFT IN INFANTS WITH CRITICAL AORTIC STENOSIS
J. Thorac. Cardiovasc. Surg., August 1, 1996; 112(2): 433 - 436.
[Abstract] [Full Text]

Home page
 Ann. Thorac. Surg.Home page
J. W. Hammon Jr
Surgical treatment of left ventricular outflow obstruction in the neonate: Profound hypothermia and circulatory arrest
Ann. Thorac. Surg., October 1, 1994; 58(4): 1274 - 1277.
[Abstract] [PDF]

Home page
 Ann. Thorac. Surg.Home page
D. D. Glower, T. M. Bashore, and C. E. Spritzer
Congenital aortic stenosis and patent ductus arteriosus in the adult
Ann. Thorac. Surg., August 1, 1992; 54(2): 368 - 370.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 1988 by The Society of Thoracic Surgeons.