ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
Patrick M. McCarthy
Victor F. Trastek
Jeffrey M. Piehler
Peter C. Pairolero
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by McCarthy, P. M.
Right arrow Articles by Pairolero, P. C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by McCarthy, P. M.
Right arrow Articles by Pairolero, P. C.

Ann Thorac Surg 1988;45:203-205
© 1988 The Society of Thoracic Surgeons

Articles

The Effectiveness of Fibrin Glue Sealant for Reducing Experimental Pulmonary Air Leak

Patrick M. McCarthy, M.D., Victor F. Trastek, M.D.*, Douglas G. Bell, B.A.*, Glenn R. Buttermann, M.S.*, Jeffrey M. Piehler, M.D., W. Spencer Payne, M.D., Louis H. Weiland, M.D., Peter C. Pairolero, M.D.

From the Sections of Thoracic and Cardiovascular Surgery and of Surgical Pathology, Mayo Clinic and Mayo Foundation, Rochester, MN

Accepted for publication October 15, 1987.

* Address reprint requests to Dr. Trastek, Mayo Clinic, 200 First St SW, Rochester, MN 55905

The effectiveness of fibrin glue as a biological sealant for pulmonary air leaks was determined in 16 dogs. A standardized pleural defect was made in the left lower lobe, and the quantity of air passing through a chest tube was assessed with a Collins respirometer. For the 8 randomly assigned control animals, the air leak decreased over 90 minutes from a mean of 1.4 L/min to a mean of 1.1 L/min (mean decrease, 19.8%). In the 8 randomly assigned fibrin glue-treated animals, the air leak decreased from a mean of 2.1 L/min to a mean of 0.5 L/min (mean decrease, 80.8%) (p < 0.0001). Postoperative evaluation of survivors disclosed no increased adhesions in the glue-treated animals and complete resorption of the glue at 3 months. We conclude that in this animal model, fibrin glue reduced the size of pulmonary air leaks in the early period after thoracotomy and did not lead to increased intrapleural adhesions.




This article has been cited by other articles:


Home page
 Ann. Thorac. Surg.Home page
A. Gonfiotti, P. F. Santini, M. Jaus, A. Janni, A. Lococo, A. R. De Massimi, A. D'Agostino, F. Carleo, M. Di Martino, V. Larocca, et al.
Safety and Effectiveness of a New Fibrin Pleural Air Leak Sealant: A Multicenter, Controlled, Prospective, Parallel-Group, Randomized Clinical Trial
Ann. Thorac. Surg., October 1, 2011; 92(4): 1217 - 1225.
[Abstract] [Full Text] [PDF]

Home page
 Eur J Cardiothorac SurgHome page
M. Kanzaki, M. Yamato, J. Yang, H. Sekine, R. Takagi, T. Isaka, T. Okano, and T. Onuki
Functional closure of visceral pleural defects by autologous tissue engineered cell sheets
Eur J Cardiothorac Surg, October 1, 2008; 34(4): 864 - 869.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
P. Tansley, F. Al-Mulhim, E. Lim, G. Ladas, and P. Goldstraw
A prospective, randomized, controlled trial of the effectiveness of BioGlue in treating alveolar air leaks
J. Thorac. Cardiovasc. Surg., July 1, 2006; 132(1): 105 - 112.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
I. Matsumoto, Y. Ohta, M. Oda, Y. Tsunezuka, M. Tamura, K. Kawakami, and G. Watanabe
Free Pericardial Fat Pads Can Act as Sealant for Preventing Alveolar Air Leaks
Ann. Thorac. Surg., December 1, 2005; 80(6): 2321 - 2324.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
M. Lois and M. Noppen
Bronchopleural Fistulas: An Overview of the Problem With Special Focus on Endoscopic Management
Chest, December 1, 2005; 128(6): 3955 - 3965.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
M. S. Allen, D. E. Wood, R. W. Hawkinson, D. H. Harpole, R. J. McKenna, G. L. Walsh, E. Vallieres, D. L. Miller, F. C. Nichols III, W. R. Smythe, et al.
Prospective randomized study evaluating a biodegradable polymeric sealant for sealing intraoperative air leaks that occur during pulmonary resection
Ann. Thorac. Surg., May 1, 2004; 77(5): 1792 - 1801.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
T. Fabian, J. A. Federico, and R. B. Ponn
Fibrin glue in pulmonary resection: a prospective, randomized, blinded study
Ann. Thorac. Surg., May 1, 2003; 75(5): 1587 - 1592.
[Abstract] [Full Text] [PDF]

Home page
 Eur J Cardiothorac SurgHome page
G. W. Herget, M. Kassa, U. N. Riede, Y. Lu, L. Brethner, and J. Hasse
Experimental use of an albumin-glutaraldehyde tissue adhesive for sealing pulmonary parenchyma and bronchial anastomoses
Eur J Cardiothorac Surg, January 1, 2001; 19(1): 4 - 9.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
H. Nomori, H. Horio, and K. Suemasu
Mixing collagen with fibrin glue to strengthen the sealing effect for pulmonary air leakage
Ann. Thorac. Surg., November 1, 2000; 70(5): 1666 - 1670.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
H. K. Kjaergard, J. H. Pedersen, M. Krasnik, U. S. Weis-Fogh, H. Fleron, and H. E. Griffin
Prevention of Air Leakage by Spraying Vivostat Fibrin Sealant After Lung Resection in Pigs
Chest, April 1, 2000; 117(4): 1124 - 1127.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
T. Kinoshita, S. Miyoshi, M. Katoh, T. Yoshimasu, M. Juri, S. Maebeya, and Y. Naito
Intrapleural Administration of a Large Amount of Diluted Fibrin Glue for Intractable Pneumothorax
Chest, March 1, 2000; 117(3): 790 - 795.
[Abstract] [Full Text] [PDF]

Home page
 Eur J Cardiothorac SurgHome page
B. A. Feito, A. M. Rath, E. Longchampt, and J. Azorin
Experimental study on the in vivo behaviour of a new collagen glue in lung surgery
Eur J Cardiothorac Surg, January 1, 2000; 17(1): 8 - 13.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
Y. Otani, Y. Tabata, and Y. Ikada
Sealing effect of rapidly curable gelatin-poly (L-glutamic acid) hydrogel glue on lung air leak
Ann. Thorac. Surg., April 1, 1999; 67(4): 922 - 926.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
H. Nomori, H. Horio, S. Morinaga, and K. Suemasu
Gelatin-resorcinol-formaldehyde-glutaraldehyde glue for sealing pulmonary air leaks during thoracoscopic operation
Ann. Thorac. Surg., January 1, 1999; 67(1): 212 - 216.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
K. Wong and P. Goldstraw
Effect of Fibrin Glue in the Reduction of Postthoracotomy Alveolar Air Leak
Ann. Thorac. Surg., October 1, 1997; 64(4): 979 - 981.
[Abstract] [Full Text]

Home page
 Ann. Thorac. Surg.Home page
A. G. Fleisher, K. G. Evans, B. Nelems, and R. J. Finley
Effect of routine fibrin glue use on the duration of air leaks after lobectomy
Ann. Thorac. Surg., January 1, 1990; 49(1): 133 - 134.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 1988 by The Society of Thoracic Surgeons.