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The Annals of Thoracic Surgery, Vol 44, 607-613, Copyright © 1987 by The Society of Thoracic Surgeons
I Garcia Andrade, R Cartier, P Panisi, K Ennabli and CM Grondin
During a 5 1/2-year period, 251 patients underwent mitral valve replacement
(MVR) at our institution: 76 had combined MVR and coronary artery bypass
grafting (CABG), and 175 without major coronary artery disease (CAD) had
isolated MVR. In-hospital mortality for MVR + CABG was 13.2% (10/76); it
was 8.6% (6/70) when patients with preoperative mechanical support were
excluded, 7.9% (5/63) for elective operations, and 8.2% (5/61) for
nonischemic mitral disease. Overall, in-hospital mortality for isolated MVR
was 6.3% (11/175); it was 4.4% (7/161) excluding patients requiring
mechanical support and 3.1% (5/157) for elective operations. Of a host of
clinical characteristics in patients with MVR +CABG, few were found to
influence in-hospital mortality: age greater than 60 years, degree of
incapacitation (New York Heart Association Functional Class IV), previous
history of myocardial infarction or congestive heart failure, cardiac
enlargement (cardiothoracic index greater than 50%), and ischemic mitral
disease (33.3% in-hospital mortality; p less than 0.05). Of the invasive
variables, only one influenced in-hospital mortality: wall motion score
greater than 10 (31.6% in-hospital mortality; p less than 0.01). Of the
operative variables studied, the number of grafts (3 or more: 33.3% in-
hospital mortality; p less than 0.05), the need for mechanical support
(47.4% in-hospital mortality; p less than 0.0001), and emergency operation
(38.5% in-hospital mortality; p less than 0.005) had a significant effect
on mortality. The type of mitral lesion, the type of prosthesis, the extent
of CAD or the completeness of revascularization, the presence of pulmonary
hypertension, and atrial fibrillation appeared to have no
influence.(ABSTRACT TRUNCATED AT 250 WORDS)
ARTICLES
Factors influencing early and late survival in patients with combined mitral valve replacement and myocardial revascularization and in those with isolated replacement
Department of Surgery, Montreal Heart Institute, Que, Canada.
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