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The Annals of Thoracic Surgery, Vol 44, 31-34, Copyright © 1987 by The Society of Thoracic Surgeons
PS Douglas, LH Edmunds, MS Sutton, R Geer, AH Harken and N Reichek
Pulmonary artery diastolic (PADP) and wedge pressures (PAWP) and left
ventricular end-diastolic pressure (LVEDP) are commonly used to estimate
left ventricular (LV) preload. To assess the ability of hemodynamic indexes
of preload to estimate anatomical preload, or LV volume, we studied 45
patients during a coronary (18 patients) or aortic valve (27 patients)
procedure and compared epicardial two- dimensional echocardiographic LV
cavity area with simultaneous measurements of PADP, PAWP, and high-fidelity
LVEDP. Pulmonary artery diastolic pressure, PAWP, and their percent change
after bypass did not correlate with absolute values (before or after
bypass) or percent change in LVEDP. Percent change in LV area correlated
weakly with percent change in PADP (r = .34, p less than .03) but not with
changes in PAWP or LVEDP. Changes were opposite in direction in 45% (PADP),
50% (PAWP), and 67% (LVEDP) of patients. In conclusion, both PADP and PAWP
were poor guides to LVEDP and neither reflected changes in LV size. Thus,
hemodynamic indexes of preload should be used with caution during cardiac
operations.
ARTICLES
Unreliability of hemodynamic indexes of left ventricular size during cardiac surgery
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