HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Author home page(s): Masafumi Higashidate Yoshinori Takanashi Tadashi Fujiwara Yasuharu Imai Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Higashidate, M. Articles by Imai, Y. Search for Related Content PubMed PubMed Citation Articles by Higashidate, M. Articles by Imai, Y.

Ann Thorac Surg 1987;43:313-317
© 1987 The Society of Thoracic Surgeons

---

Articles

A New Method to Induce Topical Cooling of the Right Atrium for Treatment of Supraventricular Tachyarrhythmia: An Experimental Study

From the Department of Pediatric Cardiovascular Surgery, Heart Institute of Japan, Tokyo Women's Medical College, Tokyo, Japan

Accepted for publication May 21, 1986.

^* Address reprint requests to Dr. Higashidate, Department of Pediatric Cardiovascular Surgery, Heart Institute of Japan, Tokyo Women's Medical College, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162 Japan

Supraventricular tachyarrhythmia (SVT) such as sinus tachycardia and atrial dysrhythmia is a life-threatening problem in the period immediately following an open-heart operation. Because of their negative inotropic effects, antiarrhythmic agents are not recommended for patients with low cardiac output syndrome. A device was developed that topically cools the right atrial surface for antiarrhythmic treatment. In experiments, this device lowered right atrial temperature and did not affect the temperature of the right ventricle or the whole body. When right atrial temperature decreased from 37° to 28°C, heart rate was reduced from 146.3 to 109.7 beats per minute (p < .001). Meanwhile, cardiac output and blood pressure remained within control levels. In the treatment of experimental SVT induced by the intravenous infusion of isoproterenol hydrochloride and by direct application of aconitine, this method worked effectively and was reproducible. The results demonstrated the beneficial effects of this method in the treatment of SVT in experimental studies and suggested its future clinical application following open-heart operations.

This article has been cited by other articles:

				F. J. Chorro, J. Guerrero, A. Ferrero, A. Tormos, L. Mainar, J. Millet, J. Canoves, J. C. Porres, J. Sanchis, V. Lopez-Merino, et al. Effects of acute reduction of temperature on ventricular fibrillation activation patterns Am J Physiol Heart Circ Physiol, December 1, 2002; 283(6): H2331 - H2340. [Abstract] [Full Text] [PDF]

				V. Parsonnet Topical Cooling of the Right Atrium Ann. Thorac. Surg., October 1, 1987; 44(4): 446 - 446. [PDF]